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Your search keyword '"María-Francisca González-Escribano"' showing total 4 results
Start Over Author "María-Francisca González-Escribano" Journal journal of translational medicine
4 results on '"María-Francisca González-Escribano"'

1. The AIRE gene and susceptibility to rheumatoid arthritis in the Spanish population

Author

Belén Torres, María Francisca González-Escribano, Alicia García, Antonio Núñez-Roldán, José Raúl García-Lozano, and M.A. Montes-Cano

Subjects
Medicine(all), Veterinary medicine, Biochemistry, Genetics and Molecular Biology(all), business.industry, lcsh:R, lcsh:Medicine, Genome-wide association study, General Medicine, Japanese population, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Negative selection, Thymocyte, Antigen, Rheumatoid arthritis, Poster Presentation, Immunology, medicine, Transcriptional regulation, business, Gene
Abstract

AIRE is a transcriptional regulator that plays a functional role in thymocyte education and negative selection by controlling the expression of peripheral antigens in thymus. This gene has been associated with the susceptibility to rheumatoid arthritis (RA) in a recent GWAS carried out in the Japanese population; nevertheless, no association has been described in Caucasian populations.

Published
2011
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2. Identification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy

Author

Madelon C. Vonk, Javier Martín, Patricia Carreira, Lorenzo Beretta, Jun Ying, Nicolas Hunzelmann, Annet Italiaander, Carmen Fonseca, Alexandre E. Voskuyl, Christopher I. Amos, María Teruel, Sandeep K. Agarwal, Monique Hinchcliff, P. García de la Peña, John Varga, Behrooz Z. Alizadeh, C.P. Simeon, Christopher P. Denton, Annika Nordin, Roger Hesselstrand, Annette Lee, Annemie J. Schuerwegh, Anna-Maria Hoffmann-Vold, Meng May Chee, Paul G. Shiels, Norberto Ortego-Centeno, Frank C. Arnett, Shervin Assassi, Jane Worthington, Benedicte A. Lie, E. De Baere, Miguel A. González-Gay, V. Fonollosa, Alexander Kreuter, Plcm van Riel, Lina-Marcela Diaz-Gallo, M. J. H. Coenen, Francisco J. García-Hernández, Rene Westhovens, Filemon K. Tan, Leonid Padyukov, R. van 't Slot, G. Riemekasten, Vanessa Smith, María Francisca González-Escribano, Roel A. Ophoff, Marie Vanthuyne, Ariane L. Herrick, Torsten Witte, B. P. C. Koeleman, Peter K. Gregersen, Olga Y. Gorlova, Jasper C A Broen, Trdj Radstake, Raffaella Scorza, Pravitt Gourh, F De Keyser, Blanca Rueda, J.M. van Laar, Rajan Madhok, Paolo Airò, Fredric Houssiau, Claudio Lunardi, J M Martin, and Maureen D. Mayes

Subjects
Medicine(all), business.industry, Biochemistry, Genetics and Molecular Biology(all), Genome-wide association study, General Medicine, Computational biology, Bioinformatics, Phenotype, General Biochemistry, Genetics and Molecular Biology, Genetic marker, Medicine, Oral Presentation, Identification (biology), business, skin and connective tissue diseases
Published
2010

3. Interleukin-6 receptor in the recent-onset rheumatoid arthritis

Author

Cristina Abad-Molina, María Francisca González-Escribano, Antonio Núñez Roldán, M.A. Montes-Cano, Alicia García, Fuensanta Torrecillas, José Raúl García-Lozano, and Sonsoles Reneses

Subjects
Alanine, Medicine(all), Α subunit, Pathology, medicine.medical_specialty, business.industry, Biochemistry, Genetics and Molecular Biology(all), lcsh:R, lcsh:Medicine, General Medicine, Cleavage (embryo), medicine.disease, Molecular biology, General Biochemistry, Genetics and Molecular Biology, Rheumatoid arthritis, Poster Presentation, Aspartic acid, Interleukin-6 receptor, medicine, Receptor, Recent onset, business
Abstract

The α subunit of the soluble receptor interleukin-6 (sIL-6R) is mainly generated by shedding of the membrane-bound form. This process is influenced by a functional polymorphism (rs 2228145 A>C) resulting in a substitution of aspartic acid to alanine (D358A) at the proteolytic cleavage site.

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4. HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population

Author

María Francisca González-Escribano, José Raúl García-Lozano, Lourdes Ortiz-Fernández, M.A. Montes-Cano, and Marta Conde-Jaldón

Subjects
Medicine(all), business.industry, Biochemistry, Genetics and Molecular Biology(all), Hla genes, General Medicine, Human leukocyte antigen, Behcet's disease, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Spanish population, Immunology, Poster Presentation, Medicine, business
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