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Start Over Author "Sofia Barbar" Journal journal of thrombosis and haemostasis : jth
3 results on '"Sofia Barbar"'

1. Physicians' compliance with the Padua Prediction Score for preventing venous thromboembolism among hospitalized medical patients

Author

Marta Milan, V. Rossetto, Sofia Barbar, Paolo Prandoni, and Valentina Vedovetto

Subjects
Male, medicine.medical_specialty, Health Knowledge, Attitudes, Practice, Attitude of Health Personnel, Risk Assessment, Decision Support Techniques, Fibrinolytic Agents, Predictive Value of Tests, Risk Factors, medicine, Humans, Prospective Studies, Practice Patterns, Physicians', Intensive care medicine, Prospective cohort study, Aged, Aged, 80 and over, Prediction score, Guideline adherence, business.industry, Anticoagulants, Hematology, Venous Thromboembolism, Awareness, Compliance (physiology), Hospitalization, Predictive value of tests, Practice Guidelines as Topic, Female, Guideline Adherence, Risk assessment, business, Venous thromboembolism, Fibrinolytic agent
Published
2013

2. Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study

Author

F, Dentali, D, Poli, U, Scoditti, M N D, Di Minno, V, De Stefano, V D, Stefano, S, Siragusa, M, Kostal, G, Palareti, M T, Sartori, E, Grandone, M C, Vedovati, W, Ageno, Anna, Falanga, Teresa, Lerede, Marina, Bianchi, Sophie, Testa, Dan, Witt, Katie, McCool, Eugenio, Bucherini, Elisa, Grifoni, Daniela, Coalizzo, Raffaella, Benedetti, Marco, Marietta, Maria, Sessa, Clara, Guaschino, Giovanni, di Minno, Antonella, Tufano, Sofia, Barbar, Alessandra, Malato, Mario, Pini, Paola, Castellini, Stefano, Barco, Marisa, Barone, Maurizio, Paciaroni, Andrea, Alberti, Giancarlo, Agnelli, Matteo, Giorgi Pierfranceschi, Petr, Dulicek, Mauro, Silingardi, Landini, Federica, Angelo, Ghirarduzzi, Eros, Tiraferri, Vincenzo, di Lazzaro, Elena, Rossi, Angela, Ciminello, Samantha, Pasca, Giovanni, Barillari, Emanuele, Rezoagli, Matteo, Galli, Alessandro, Squizzato, Alberto, Tosetto, Policarpo, D, Dentali, F, Poli, D, Scoditti, U, di Minno, M, De Stefano, V, Siragusa, S, Kostal, M, Palareti, G, Sartori, M, Grandone, E, Vedovati, M, Ageno, W, Di Minno, M, Stefano, V, Falanga, A, Lerede, T, Bianchi, M, Testa, S, Witt, D, Mccool, K, Bucherini, E, Grifoni, E, Coalizzo, D, Benedetti, R, Marietta, M, Sessa, M, Guaschino, C, di Minno, G, Tufano, A, Barbar, S, Malato, A, Pini, M, Castellini, P, Barco, S, Barone, M, Paciaroni, M, Alberti, A, Agnelli, G, Giorgi Pierfranceschi, M, Dulicek, P, Silingardi, M, Federica, L, Ghirarduzzi, A, Tiraferri, E, di Lazzaro, V, Rossi, E, Ciminello, A, Pasca, S, Barillari, G, Rezoagli, E, Galli, M, Squizzato, A, Tosetto, A, Poli, D., Scoditti, U., DI MINNO, Matteo, Stefano, V. D., Siragusa, S., Kostal, M., Palareti, G., Sartori, M. T., Grandone, E., Vedovati, M. C., and Ageno, W. for the CEVETIS Study Group

Subjects
Adult, Male, medicine.medical_specialty, Anticoagulant treatment, Cerebral vein thrombosis, Mortality, Recurrence, Cerebral Veins, Cohort Studies, Female, Humans, Middle Aged, Thrombosis, Internal medicine, medicine, Risk of mortality, MED/41 - ANESTESIOLOGIA, business.industry, Incidence (epidemiology), Cerebral Vein thrombosi, Hazard ratio, Cerebral Vein, Retrospective cohort study, Hematology, medicine.disease, Confidence interval, Surgery, cerebral vein thrombosis, Settore MED/15 - MALATTIE DEL SANGUE, Thrombosi, Cohort, Cohort Studie, business, Human, Cohort study
Abstract

Summary. Background: Little information is available on the long-term clinical outcome of cerebral vein thrombosis (CVT). Objectives and methods: In an international, retrospective cohort study, we assessed the long-term rates of mortality, residual disability and recurrent venous thromboembolism (VTE) in a cohort of patients with a first CVT episode. Results: Seven hundred and six patients (73.7% females) with CVT were included. Patients were followed for a total of 3171 patient-years. Median follow-up was 40 months (range 6, 297 months). At the end of follow-up, 20 patients had died (2.8%). The outcome was generally good: 89.1% of patients had a complete recovery (modified Rankin Score [mRS] 0–1) and 3.8% had a partial recovery and were independent (mRS 2). Eighty-four per cent of patients were treated with oral anticoagulants and the mean treatment duration was 12 months. CVT recurred in 31 patients (4.4%), and 46 patients (6.5%) had a VTE in a different site, for an overall incidence of recurrence of 23.6 events per 1000 patient-years (95% confidence Interval [CI] 17.8, 28.7) and of 35.1 events/1000 patient-years (95% CI, 27.7, 44.4) after anticoagulant therapy withdrawal. A previous VTE was the only significant predictor of recurrence at multivariate analysis (hazard ratio [HR] 2.70; 95% CI 1.25, 5.83). Conclusions: The long-term risk of mortality and recurrent VTE appears to be low in patients who survived the acute phase of CVT. A previous VTE history independently predicts recurrent events.

Published
2012

3. A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score

Author

Paolo Prandoni, Antonio Pagnan, Franco Noventa, B. Brandolin, Marica Perlati, V. Rossetto, E. De Bon, Sofia Barbar, A. Ferrari, and Daniela Tormene

Subjects
Adult, Male, Risk, medicine.medical_specialty, MEDLINE, Hemorrhage, Risk Assessment, Cohort Studies, Internal medicine, Medicine, Humans, cardiovascular diseases, Prospective Studies, Prospective cohort study, Aged, Aged, 80 and over, business.industry, Hazard ratio, Hematology, Venous Thromboembolism, Middle Aged, equipment and supplies, medicine.disease, Thrombosis, Pulmonary embolism, Surgery, Hospitalization, Treatment Outcome, Italy, Female, business, Risk assessment, Venous thromboembolism, Cohort study
Abstract

Summary. Background: Prophylaxis of venous thromboembolism (VTE) in hospitalized medical patients is largely underused. We sought to assess the value of a simple risk assessment model (RAM) for the identification of patients at risk of VTE. Methods: In a prospective cohort study, 1180 consecutive patients admitted to a department of internal medicine in a 2-year period were classified as having a high or low risk of VTE according to a predefined RAM. They were followed-up for up to 90 days to assess the occurrence of symptomatic VTE complications. The primary study outcome was to assess the adjusted hazard ratio (HR) of VTE in high-risk patients who had adequate in-hospital thromboprophylaxis in comparison with those who did not, and that of VTE in the latter group in comparison with low-risk patients. Results: Four hundred and sixty-nine patients (39.7%) were labelled as having a high risk of thrombosis. VTE developed in four of the 186 (2.2%) who received thromboprophylaxis, and in 31 of the 283 (11.0%) who did not (HR of VTE, 0.13; 95% CI, 0.04–0.40). VTE developed also in two of the 711 (0.3%) low-risk patients (HR of VTE in high-risk patients without prophylaxis as compared with low-risk patients, 32.0; 95% CI, 4.1–251.0). Bleeding occurred in three of the 186 (1.6%) high-risk patients who had thromboprophylaxis. Conclusions: Our RAM can help discriminate between medical patients at high and low risk of VTE. The adoption of adequate thromboprophylaxis in high-risk patients during hospitalization leads to longstanding protection against thromboembolic events with a low risk of bleeding.

Published
2010

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