1. Apatite formation abilities of various carrageenan gels in simulated body environment
- Author
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Ryo Nakata, Yumi Morita, Eiichi Ishida, Ryota Iwatsuki, Chikara Ohtsuki, and Toshiki Miyazaki
- Subjects
Materials science ,Aqueous solution ,animal structures ,Simulated body fluid ,animal diseases ,Inorganic chemistry ,Nucleation ,General Chemistry ,respiratory system ,Simulated body fluid (SBF) ,Condensed Matter Physics ,Carrageenan ,Apatite ,carbohydrates (lipids) ,chemistry.chemical_compound ,Organic–inorganic hybrid ,chemistry ,Chemical engineering ,visual_art ,Self-healing hydrogels ,Materials Chemistry ,Ceramics and Composites ,visual_art.visual_art_medium - Abstract
Organic–inorganic hybrids with apatite-forming abilities in physiological environments offer possibilities for building flexible bone-bonding bioactive materials; several functional groups are known to induce apatite nucleation. Here, bioactive organic–inorganic hybrids from κ-carrageenan and λ-carrageenan containing sulfonic groups were prepared. Carrageenan hydrogels were made by cross-linking with CaCl2. The apatite-forming abilities of each kind of carrageenan hydrogel were examined using simulated body fluid (SBF); λ-carrageenan was found to be superior to κ-carrageenan for this purpose. The former swelled significantly in aqueous conditions, releasing a large amount of Ca2+ ions into the SBF, contributing to rapid apatite formation.
- Published
- 2010