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In this discussion I have covered the relationship of toxicity to hazard, and I have argued that normally expected residues of pesticides on forage are practically never a hazard to livestock, but that some of the pesticides are stored in the tissues of livestock and excreted in their milk, creating a potential hazard to people. This hazard can be avoided by carefully following label instructions as to dosage and proper intervals which must occur between treatment and harvest of slaughter. I have indicated that chemical analyses are of virtually no value for diagnostic purposes. I have pointed out that all the toxicological information developed for a given compound can be utilized only if the manufacturer, formulator, and consumer contribute equally to safe, intelligent usage. The manufacturers and formulators must prepare the compounds in stable, readily usable form, and devise labels for the final product, which will clearly define the intended uses and limitations of the product. The consumer must read the label and adhere strictly to the suggestions found there. I believe that the rational use of pesticides in agriculture is essential if we are to maintain maximum productivity in the face of constantly shrinking farm and ranch land and an exploding population. I believe that these materials can be, and are being, used with complete safety to man and animals when label instructions are followed. [ABSTRACT FROM AUTHOR]