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It is generally recognized today that cortisone used internally can be of great value in helping patients through severe and distressing phases of certain acute dermatoses. Patients with acute, incapacitating but ordinarily self-limited eruptions, such as severe, widespread, eczematous contact dermatitis, acute urticaria, angioneurotic edema, and certain drug reactions, can quite often be relieved of the majority of their troubles without interfering with their progress toward natural recovery. 1 There is also a quite general agreement that for properly selected, otherwise healthy patients this form of short-term administration of cortisone, lasting from several days to a week or so, usually carries little risk of serious untoward effects. Another common field of usefulness of cortisone in dermatology is its long-term, more or less continuous use internally in chronic or chronic recurrent dermatoses. 2 The dermatoses in this group can be divided into two subgroups: first, those not ordinarily fatal but in

The medical profession may be divided into three classes, with reference to their different views of morphinism and its treatment: 1. Those who consider that the addiction has produced a diseased condition of the nerve-centers and that by a well-directed, scientific treatment the patient may be restored to health. 2. Those who believe that the continuous use of morphin produces such a pathologic condition of the nerve-centers that treatment is of no avail, that is, "once in morphin always in morphin." 3. Those who look with little sympathy on those unfortunates who have become accustomed to the use of narcotic drugs, and who seem to consider the use of the hypodermic a mere habit which could be as readily discontinued as could a physician cease toying with his watchchain or mustache while talking at the bedside of his patients. In other words, they think that if the person desires to

The apparatus herein described was built in July 1931 to meet in a practical way the well established needs of the premature or the full term new-born infant suffering from respiratory or circulatory embarrassment; namely, (1) carbon dioxide-oxygen mixture1for stimulation of the respiratory centers, (2) oxygen2to combat anoxemia, (3) external heat to maintain body temperature, (4) easy accessibility to provide feeding and nursing care with a minimum of handling and without removing the baby from the atmosphere of oxygen, and (5) full visibility to insure careful watching. Continuous use of the apparatus in the nursery of the Henry Ford Hospital for five years has proved its value in treating cases of asphyxia neonatorum, intracranial hemorrhage, atelectasis, congenital heart disease, blood dyscrasias, excessive mucus or any other condition that might cause cyanosis or anoxemia. While statistics to prove it are difficult to gather, it is the opinion of those

It is extraordinary that, after continuous use for 130 years, the study of the action of digitalis retains so vital an interest, not only in clinical medicine, but also in experimental pharmacology. This interest has been quickened by the fundamental investigations of James Mackenzie on the mechanism of the heart beat and by the construction by Einthoven of a galvanometer suitable for registering the action currents of the heart. I mention James Mackenzie especially, because in the bewildering variety of studies which he has stimulated he has, almost alone, kept in view the essential objects of investigation in the domain of cardiovascular disease. These are, first, the study of symptoms suggesting the presence of incipient heart disease, and second, the study of the mechanism of heart failure and its treatment. His study of the disturbed rhythms of the heart was undertaken to ascertain whether they had a vital relation to

Soon after the release to the profession of Ehrlich's first synthetic arsenic product, the ultra-enthusiastic gave forth the cry to the carrier of the Spirochaeta pallida that the salvator hominum had been found. The extremely conservative held the more tenaciously to mercury, the approved therapy of centuries, and pessimistically pictured the dangers of salvarsan. While as yet our conclusions may not be beyond the pale of dispute, it may prove valuable to make a reckoning of the experience of four years in the continuous use of the powerful drug. That a new era in the treatment of syphilis has been entered there can be no doubt. The discovery by the lamented Schaudinn, the dark-field microscope and the ingenious adaptation by Wassermann of the Bordet-Gengou biochemical reaction have set our feet on firm rock in our determination of skin and visceral syphilis. Colles' law has been given the lie; Profeta's dogma

A case of respiratory poliomyelitis and peripheral paralysis was reported in The Journal (113:1806 [Nov. 11] 1939) in which the patient had depended on a respirator for eight years. This dependence continued 10 1/2 more years until the patient died, on April 17, 1950. During the 18 1/2 year period that he was ill, the patient stayed in Vassar Brothers Hospital, Poughkeepsie, N. Y. As the report covering the first eight years is presented here in the briefest outline, the original report should be referred to for details.REPORT OF A CASE B. S., then 13 years old, was admitted to the medical service of Vassar Brothers Hospital on the fifth day of an acute attack of poliomyelitis, with complete paralysis of all four extremities, with the exception of the toes and the fingers of the left hand. Twelve hours later, dyspnea and cyanosis necessitated the continuous use of