1. Changes in Medical Therapy and Lifestyle After Anatomical or Functional Testing for Coronary Artery Disease.
- Author
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Ladapo, Joseph A, Hoffmann, Udo, Lee, Kerry L, Coles, Adrian, Huang, Megan, Mark, Daniel B, Dolor, Rowena J, Pelberg, Robert A, Budoff, Matthew, Sigurdsson, Gardar, Severance, Harry W, and Douglas, Pamela S
- Subjects
Humans ,Obesity ,Aspirin ,Adrenergic beta-Antagonists ,Platelet Aggregation Inhibitors ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,Angiotensin-Converting Enzyme Inhibitors ,Echocardiography ,Stress ,Exercise Test ,Exercise ,Follow-Up Studies ,Smoking ,Patient Compliance ,Life Style ,Aged ,Middle Aged ,Female ,Male ,Overweight ,Coronary Artery Disease ,Randomized Controlled Trials as Topic ,Angiotensin Receptor Antagonists ,Computed Tomography Angiography ,Diet ,Healthy ,angina ,coronary disease ,diagnosis ,prevention ,Cardiovascular ,Prevention ,Heart Disease ,Heart Disease - Coronary Heart Disease ,Clinical Research ,Nutrition ,Atherosclerosis ,Cardiorespiratory Medicine and Haematology - Abstract
BackgroundDiagnostic testing in the care of patients newly presenting with symptoms suggestive of coronary artery disease may influence risk factor management, independent of test type or test results. However, little is known about changes in medications and lifestyle after anatomical or functional testing.Methods and resultsWe examined what factors influenced preventive medical therapy and lifestyle practices at 60 days among 10 003 symptomatic patients (53% women; mean age 61 years) randomly assigned to anatomical testing with coronary computed tomographic angiography or functional testing (NCT01174550). We also assessed the association of preventive changes with major cardiovascular events. There were no differences in medications/lifestyle at baseline. At 60 days, relative to baseline, the computed tomographic angiography strategy was associated with a higher proportion of patients newly initiating aspirin (11.8% versus 7.8%), statins (12.7% versus 6.2%), and β-blockers (8.1% versus 5.3%), compared to functional testing (P
- Published
- 2016