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Your search keyword '"Townend, Jonathan N"' showing total 9 results
Start Over Author "Townend, Jonathan N" Journal journal of the american college of cardiology
9 results on '"Townend, Jonathan N"'

1. Coronary Atherosclerotic Plaque Activity and Risk of Myocardial Infarction

Author

Wang, Kang-Ling, primary, Balmforth, Craig, additional, Meah, Mohammed N., additional, Daghem, Marwa, additional, Moss, Alastair J., additional, Tzolos, Evangelos, additional, Kwiecinski, Jacek, additional, Molek-Dziadosz, Patrycja, additional, Craig, Neil, additional, Bularga, Anda, additional, Adamson, Philip D., additional, Dawson, Dana K., additional, Arumugam, Parthiban, additional, Sabharwal, Nikant K., additional, Greenwood, John P., additional, Townend, Jonathan N., additional, Calvert, Patrick A., additional, Rudd, James H.F., additional, Verjans, Johan W., additional, Berman, Daniel S., additional, Slomka, Piotr J., additional, Dey, Damini, additional, Mills, Nicholas L., additional, van Beek, Edwin J.R., additional, Williams, Michelle C., additional, Dweck, Marc R., additional, and Newby, David E., additional

Published
2024
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9. Effect of Spironolactone on Left Ventricular Mass and Aortic Stiffness in Early-Stage Chronic Kidney Disease A Randomized Controlled Trial

Author

Edwards, Nicola C., Steeds, Richard P., Stewart, Paul M., Ferro, Charles J., and Townend, Jonathan N.

Subjects
arterial stiffness, renin-angiotensin-aldosterone system, spironolactone, left ventricular mass, chronic kidney disease
Abstract

ObjectivesWe sought to determine whether the addition of spironolactone to angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) improves left ventricular mass and arterial stiffness in early-stage chronic kidney disease (CKD).BackgroundChronic kidney disease is associated with a high risk of cardiovascular disease and a high prevalence of left ventricular hypertrophy and arterial stiffness that confer an adverse prognosis. It is believed that these abnormalities are in part a result of activation of the renin-angiotensin-aldosterone system.MethodsAfter an active run-in phase with spironolactone 25 mg once daily, 112 patients with stage 2 and 3 CKD with good blood pressure control (mean daytime ambulatory blood pressure

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