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Your search keyword '"Cristi L. Galindo"' showing total 5 results
Start Over Author "Cristi L. Galindo" Journal journal of the american college of cardiology
5 results on '"Cristi L. Galindo"'

1. ALTERED SERCA2A EXPRESSION IN MITRAL VALVE LEAFLETS IN CHRONIC ISCHEMIC MITRAL REGURGITATION

Author

Ashish S. Shah, Keki R. Balsara, James B. Atkinson, Richard J. Gumina, Alexandra Foshage, Tarek S. Absi, Cristi L. Galindo, Yan Ru Su, Kelsey Tomasek, Christopher Groark, and Clayton A. Kaiser

Subjects
medicine.medical_specialty, Ischemic mitral regurgitation, business.industry, Adaptive change, Structural remodeling, medicine.anatomical_structure, Mitral valve, Internal medicine, Gene expression, cardiovascular system, Cardiology, medicine, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business
Abstract

Mitral valve (MV) leaflets in ischemic mitral regurgitation (IMR) undergo structural remodeling associated with adaptive changes. We hypothesized that the gene expression profiles of MV leaflets from patients with IMR are distinct from normal MVs. MVs were obtained from 7 patients (4M, age= 70.4±8

Published
2019

2. RIGHT VENTRICLE TRANSCRIPTIONAL PROFILING IN HUMAN HEART FAILURE

Author

Travis Clark, Thomas G. Di Salvo, Yan Guo, Anna R. Hemnes, Evan L. Brittain, Tarek bsi, Douglas B. Sawyer, Cristi L. Galindo, Simon Maltais, and Yan Ru Su

Subjects
Transcriptome, medicine.anatomical_structure, Ventricle, business.industry, cDNA library, medicine, Human heart, Computational biology, business, Cardiology and Cardiovascular Medicine
Abstract

The right ventricular (RV) transcriptome in human heart failure (HF) has not been widely reported. We performed RNAseq (30M target reads/cDNA library, paired-end 50 bp sequencing by Illumina HiSeq 25009) on 5 unused donor RVs (DON) and 22 explanted HF RVs. We used a novel sum of ranks approach

Published
2014
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3. OSTEOPONTIN AND BRAIN DERIVED NEUROTROPHIC FACTOR: BIOMARKERS OF CARDIOVASCULAR DISEASE IN DUCHENNE MUSCULAR DYSTROPHY

Author

Cristi L. Galindo, W. Bryan Burnette, Joe N. Kornegay, Larry W. Markham, Jonathan H. Soslow, Holly M. Smith, Bruce M. Damon, and Douglas B. Sawyer

Subjects
musculoskeletal diseases, Brain-derived neurotrophic factor, Pathology, medicine.medical_specialty, biology, business.industry, Duchenne muscular dystrophy, Cardiomyopathy, macromolecular substances, Disease, medicine.disease, Brain natriuretic peptide, Troponin, stomatognathic system, medicine, biology.protein, Physical therapy, Osteopontin, Cardiology and Cardiovascular Medicine, business, Cause of death
Abstract

Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD). Biomarkers such as troponin and brain natriuretic peptide are unable to reliably assess disease severity. We previously demonstrated abnormalities of osteopontin (OPN) and brain derived neurotrophic factor (BDNF) in

Published
2016

4. ISCHEMIC VERSUS NON-ISCHEMIC RIGHT VENTRICULAR TRANSCRIPTOME IN END-STAGE HUMAN HEART FAILURE

Author

Tarek bsi, Cristi L. Galindo, Simon Maltais, Yan Ru Su, Thomas G. Di Salvo, Douglas B. Sawyer, and Yan Guo

Subjects
Transcriptome, medicine.medical_specialty, cDNA library, business.industry, Internal medicine, Cardiology, medicine, Human heart, Non ischemic, Stage (cooking), Cardiology and Cardiovascular Medicine, business, NISCH
Abstract

The right ventricular (RV) transcriptome in ischemic (ISCH) vs. non-ischemic (NISCH) end-stage human heart failure (HF) has not been widely studied. We performed RNAseq (30M target reads/cDNA library, paired-end 50 bp sequencing by Illumina HiSeq 25009) on RV tissue obtained from 11 ISCH and 11

Published
2014

5. RIGHT VENTRICULAR MATRISOME IN HUMAN HEART FAILURE

Author

Douglas B. Sawyer, Simon Maltais, Travis Clark, Anna R. Hemnes, Thomas G. Di Salvo, Su Yan Ru, Tarek S. Absi, Yan Guo, and Cristi L. Galindo

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Cardiology, medicine, Human heart, Cardiology and Cardiovascular Medicine, business
Published
2014

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