1. International Prospective Registry of Acute Coronary Syndromes in Patients With COVID-19
- Author
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Nicholas D. Palmer, Marija Vavlukis, Anthony H. Gershlick, Héctor Hugo Escutia-Cuevas, Mzee Ngunga, Otilia Tica, Chris P Gale, Parham Sadeghipour, Pilar Jiménez-Quevedo, Imad Meray, Luciano Candilio, Ghada Kazamel, Gregg W. Stone, Andrew Morrow, Minhaj Arefin, Colin Berry, Sharon Kean, Nick Curzen, Alim Namitokov, Peter Ludman, Jacques Mansourati, Federico Ariel Sanchez, Stephen P. Hoole, Marek Roik, Aly Saad, Albert Ariza-Solé, Shankar Sangaraju, Adriano Caixeta, Jianhua Wu, Gianfranco Sinagra, Manel Sabaté, Thomas A Kite, Steven Lindsay, Iqbal S. Malik, Angel M. Iniesta, Flavien Vincent, Bernard J. Gersh, Vinoda Sharma, and Stefano Savonitto
- Subjects
Male ,medicine.medical_specialty ,Acute coronary syndrome ,NSTE-ACS, non–ST-segment elevation acute coronary syndrome ,medicine.medical_treatment ,Population ,Infarction ,030204 cardiovascular system & hematology ,Revascularization ,Coronary Angiography ,acute coronary syndrome ,03 medical and health sciences ,non–ST-segment elevation myocardial infarction ,0302 clinical medicine ,medicine ,Humans ,030212 general & internal medicine ,Myocardial infarction ,Hospital Mortality ,Registries ,education ,Stroke ,Original Investigation ,COVID-19, coronavirus disease 2019 ,Aged ,education.field_of_study ,PCI, percutaneous coronary intervention ,business.industry ,Cardiogenic shock ,cardiogenic shock ,COVID-19 ,STEMI, ST-segment elevation myocardial infarction ,Middle Aged ,medicine.disease ,ST-segment elevation myocardial infarction ,N-STEMI, non–ST-segment elevation myocardial infarction ,Heart failure ,Emergency medicine ,MI, myocardial infarction ,ACS, acute coronary syndrome ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Published data suggest worse outcomes in acute coronary syndrome (ACS) patients and concurrent coronavirus disease 2019 (COVID-19) infection. Mechanisms remain unclear. Objectives The purpose of this study was to report the demographics, angiographic findings, and in-hospital outcomes of COVID-19 ACS patients and compare these with pre–COVID-19 cohorts. Methods From March 1, 2020 to July 31, 2020, data from 55 international centers were entered into a prospective, COVID-ACS Registry. Patients were COVID-19 positive (or had a high index of clinical suspicion) and underwent invasive coronary angiography for suspected ACS. Outcomes were in-hospital major cardiovascular events (all-cause mortality, re–myocardial infarction, heart failure, stroke, unplanned revascularization, or stent thrombosis). Results were compared with national pre–COVID-19 databases (MINAP [Myocardial Ischaemia National Audit Project] 2019 and BCIS [British Cardiovascular Intervention Society] 2018 to 2019). Results In 144 ST-segment elevation myocardial infarction (STEMI) and 121 non–ST-segment elevation acute coronary syndrome (NSTE-ACS) patients, symptom-to-admission times were significantly prolonged (COVID-STEMI vs. BCIS: median 339.0 min vs. 173.0 min; p, Central Illustration
- Published
- 2021