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Start Over Author "Weibel, Stephen C." Journal journal of the american chemical society
1 results on '"Weibel, Stephen C."'

1. Carbon-on-metal films for surface plasmon resonance detection of DNA arrays

Author

Lockett, Matthew R., Weibel, Stephen C., Phillips, Margaret F., Shortreed, Michael R., Bin Sun, Corn, Robert M., Hamers, Robert J., Cerrina, Franco, and Smith, Lloyd M.

Subjects
DNA-ligand interactions -- Analysis, Plasmons (Physics) -- Research, Dielectric films -- Composition, Thin films -- Composition, Chemistry
Abstract

A novel carbon-on-metal thin film substrate is described, which has enabled surface plasmon resonance detection with photolithographically fabricated DNA arrays for the analysis of biomolecular interactions. The utility of the technology is shown in the analysis of specific DNA-DNA and DNA-protein binding interactions and this group has used new substrates to determine the secondary structure of RNA molecules.

Published
2008

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