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The design and synthesis of hyperbranched molecules are described that can be imaged in vivo by using [super 19]F magnetic resonance imaging (MRI). The polymers are cytocompatible following chain extension with PEGMA and the functionalization of these macromolecules is achieved with accessible and correct ligand presentation.

The reversible aggregation of a specific bacterial strain controlled by thermoresponsive glycopolymers as a step toward robust and reusable cell-sensing materials is described. The analysis has shown that it is possible to place bacterial aggregation under external control by combining thermoresponsive polymer chains, accessible functionality and choice of sugar moiety.

The first example wherein a multisubunit and multifunctional DNA restriction-modification (R-M) enzyme is regulated by a theromoresponsive polymer 'switch' conjugated at a subunit distal to the DNA recognition and restriction sites is presented. The studies reveal that in this polymer-enzyme hybrid, the changes in DNA methylation operations of the R-M enzyme follow the temperature-mediated phase transitions of the polymer.

A study relating to molecular imprinting research describes the interaction of a series of homologous sterols with their respective imprinted polymers containing one or two boronic acid residues in the recognition sites. The covalent technique of imprinting was selected as the most appropriate for this experiment because it does not require functional polymers to be present in the polymerization mixture in excess. Experimental methodology and results are presented.

The article offers information on the results of the study on the design and synthesis of hyperbranched molecules that can be seen in the living organism using the polymeric 19F magnetic resonance imaging (MRI). It mentions that the functionalization of the macromolecules can be attained in a facile manner with accessible and correct ligand presentation. It notes that the hyperbranched polymers serve as the new generation tracking and targeting MRI contrast agents.

The article describes ion-sensitive isothermal responsive polymers wherein the side-chain functionality normally used for aqueous solubility is utilized as an ion-responsive component. According to the authors, the ionic response allows a phase transition to be triggered in thermosensitive polymers without a temperature change. They add that the effect of a polymer response to the presence of ions should lead to formation or destruction of supramolecular architectures.