Search

Your search keyword '"Mohanty, Debasisa"' showing total 1 results
Start Over Author "Mohanty, Debasisa" Journal journal of the american chemical society Publisher american chemical society

Refine your results

1 results on '"Mohanty, Debasisa"'

1. Promiscuous Fatty Acyl CoA Ligases Produce Acyl-CoA and Acyl-SNAC Precursors for Polyketide Biosynthesis.

Author

Arora, Pooja, Vats, Archana, Saxena, Priti, Mohanty, Debasisa, and Gokhale, Rajesh S.

Subjects
*POLYKETIDES, *BIOSYNTHESIS, *NATURAL products, *GENETIC engineering, *BIOCHEMICAL engineering, *COENZYMES
Abstract

This article focuses on the precursors of polyketide biosynthesis. The study of bioactive natural products has undergone rapid advancement with the cloning and sequencing of large numbers of gene clusters. Polyketide synthases utilize acyl-coenzyme A (CoA) precursors and synthesize polyketides by repetitive decarboxylative condensations. The potential of these proteins to produce varied CoA precursors and their utilization in polyketide biosynthesis have not been investigated. Acyl-activating enzymes proteins provide an attractive route to expand the precursors available for polyketide biosynthesis.

Published
2005
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results