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Your search keyword '"Moffatt, Lauren T."' showing total 12 results
Start Over Author "Moffatt, Lauren T." Journal journal of surgical research
12 results on '"Moffatt, Lauren T."'

3. Assessing Factor V Antigen and Degradation Products in Burn and Trauma Patients

Author

Keyloun, John W., primary, Le, Tuan D., additional, Orfeo, Thomas, additional, Brummel-Ziedins, Kathleen E., additional, Bravo, Maria C., additional, Kaye, Matthew D., additional, Bourne, Dana E., additional, Carney, Bonnie C., additional, Freeman, Kalev, additional, Mann, Kenneth G., additional, Pusateri, Anthony E., additional, Shupp, Jeffrey W., additional, McLawhorn, Melissa M., additional, Moffatt, Lauren T., additional, Callcut, Rachael A., additional, Cohen, Mitchell J., additional, Petzold, Linda R., additional, Varner, Jeffrey D., additional, Bravo, Maria Cristina, additional, Gautam, Aarti, additional, Hammamieh, Rasha, additional, and Jett, Marti, additional

Published
2022
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9. In-depth analysis of clotting dynamics in burn patients

Author

Tejiram, Shawn, primary, Brummel-Ziedins, Kathleen E., additional, Orfeo, Thomas, additional, Mete, Mihriye, additional, Desale, Sameer, additional, Hamilton, Brittany N., additional, Moffatt, Lauren T., additional, Mann, Kenneth G., additional, Tracy, Russell P., additional, and Shupp, Jeffrey W., additional

Published
2016
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12. Plasma Inclusive Resuscitation Is Not Associated With Coagulation Profile Changes in Burn Patients.

Author

Mathew SK, Le TD, Pusateri AE, Pinto DN, Carney BC, McLawhorn MM, Tejiram S, Travis TE, Moffatt LT, and Shupp JW

Abstract

Introduction: Dynamically titrated crystalloids are the standard of care for burn shock resuscitation. There are theoretical concerns that the adjunctive use of allogeneic plasma may perturb the patient's coagulation and inflammation status deleteriously. It was hypothesized that plasma-inclusive resuscitation (PIR) would not be associated with prothrombotic changes relative to baseline after thermal injury., Methods: Patients admitted to a regional burn center who were treated with PIR as part of their burn resuscitation were enrolled. Whole blood samples were analyzed prospectively via rapid thromboelastography and rotational thromboelastometry to assess for coagulopathy at four time points throughout their acute burn resuscitation. The mixed-effect model for repeated measures followed by Tukey's post hoc test for comparisons was used to examine group differences., Results: There were 35 patients in the analysis. Most were male (74.3%) with a median age of 43 y (32-55), concomitant inhalation injury of 28.6%, total body surface area burn size of 34% (27%-48.5%), and the overall mortality of the cohort was 28.6%. There were no transfusion reactions or thrombotic events. There were no differences in thromboelastography or rotational thromboelastometry parameters overall or when stratified by mortality, total body surface area burn, and inhalation injury. There were no significant differences between the fibrinolytic phenotypes over time., Conclusions: Data suggest that PIR was not associated with prothrombotic or lytic changes in burn patients relative to baseline. Further research is needed to confirm these findings and evaluate efficacy of PIR in acute burn resuscitation., (Published by Elsevier Inc.)

Published
2024
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