1. Preoperative cancer cachexia and short-term outcomes following surgery
- Author
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Annette Walder, David H. Berger, Meredith C. Mason, Jose M. Garcia, S. Sansgiry, and Daniel A. Anaya
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cachexia ,Population ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Weight loss ,Neoplasms ,medicine ,Humans ,Prospective Studies ,education ,Prospective cohort study ,Aged ,Aged, 80 and over ,education.field_of_study ,Performance status ,business.industry ,Odds ratio ,Middle Aged ,medicine.disease ,Surgery ,Logistic Models ,Treatment Outcome ,030220 oncology & carcinogenesis ,Multivariate Analysis ,Preoperative Period ,Female ,030211 gastroenterology & hepatology ,Underweight ,medicine.symptom ,business ,Body mass index - Abstract
Background Cancer cachexia is an important measure of physiologic reserve associated with worse survival and represents an actionable factor for the cancer population. However, the incidence of cachexia in surgical cancer patients and its impact on postoperative outcomes are currently unknown. Methods A prospective cohort study enrolling patients having elective cancer surgery (2012-2014) at a Veterans Affairs tertiary referral center. Preoperative cancer cachexia (weight loss ≥5% over 6-mo period before surgery) was the predictor of interest. The primary outcome was 60-d postoperative complications (VA Surgical Quality Improvement Program). Patients were grouped by body mass index (BMI) category (
- Published
- 2016
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