1. Vitamin D levels and breast cancer characteristics: Findings in patients from Saudi Arabia.
- Author
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Abulkhair, Omalkhair, Saadeddin, Ahmed, Makram, Olaa, Gasmelseed, Ahmed, Pasha, Tabrez, Shehata, Hussam, and Fakhoury, Hana M.
- Subjects
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PHYSIOLOGICAL effects of vitamin D , *BREAST cancer risk factors , *BREAST cancer patients , *BLOOD serum analysis , *PUBLIC health - Abstract
Inverse relationship between vitamin D status and risk of breast cancer has been previously reported in the literature. We conducted this study to determine the association between vitamin D levels and breast cancer characteristics in patients from Saudi Arabia. Newly diagnosed breast cancer patients ( N = 406) were recruited. Serum levels of 25-hydroxyvitamin D [25 (OH) D] were measured at baseline. A significantly higher percentage of patients with triple negative status (18%) had 25 (OH) D levels ≤25 nmol/L, compared to only 8% with 25 (OH) D levels >25 nmol/L ( p = 0.009). Patients with 25 (OH) D levels ≤25 nmol/L were 2.54 times more likely to present with triple negative status compared to those with 25 (OH) D levels >25 nmol/L ( p = 0.02). Our findings suggest an association between low 25 (OH) D levels and increased risk of triple negative breast cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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