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The Guanchín Formation is a sedimentary unit that was deposited during the Andean orogeny and is preserved in the Fiambalá Basin in NW Argentina. It records an advanced stage of the broken-foreland evolution in a transitional zone between the morphotectonic domains of the Precordillera, the Sistema de Famatina, the Western Sierras Pampeanas, and the southern Puna. Furthermore, it preserves a record of Late Miocene explosive volcanism that is common in all the foreland basins in this Andean segment. The Guanchín Formation was studied at Cuesta Loro Huasi and Guanchíncito sections, where seven facies associations (FA) were recognized. These represent ephemeral sandy braided fluvial systems with thin mud floodplains (FA1), sheetflow-dominated sandy-tuffaceous alluvial plain (FA2), perennial sandy braided fluvial system (FA3), fine-grained alluvial plain built up by unconfined flows and less terminal splays (FA4), sheetflow-dominated sandy alluvial plain (FA5), and sandy-gravelly (FA6) and sandy-dominated (FA7) braided fluvial system, arranged in chronological order from oldest to youngest. To date the formation, zircon U/Pb ages from tephras were obtained from the Cuesta Loro Huasi section, which yielded depositional ages of 6.10 ± 0.07, 5.89 ± 0.09, 5.60 ± 0.06, and 5.20 ± 0.05 Ma, while a fifth sample from the Guanchíncito section yielded an age of 3.26 ± 0.05 Ma. Additionally, detrital zircon analyses were performed to infer sediment provenance and constrain the maximum depositional age of sedimentary units. These data combined with paleoenvironmental analysis and clast compositions in conglomerates suggest that the Western Sierras Pampeanas had been uplifted around ∼6 Ma. By this time the drainage was dissipated as a distributary fluvial system (DFS) under semiarid climatic conditions, which received sediments from northern, eastern, and to a lesser extent from western sources. Around ∼3 Ma the basin started to receive coarse-grained sediments of braided fluvial systems (FA6 and 7) indicating a closer proximity to the Pampean sources areas. The Guanchín Formation records an overall progradational trend manifested through two minor progradational cycles, each one controlled by changes in the equilibrium profile and accommodation space of the basin. This trend is likely associated with a basinward increase in the subsidence rate or enhanced water availability in the headwaters, potentially linked to tectonic uplift in the eastern and/or northern ranges, including the final uplift of the southern Puna. Since previous works placed the deposition of the overlying Rodado de la Puna Formation deposition began at 4 Ma, these news ages suggest the top of the Guanchin Formation is younger than previously thought. • Guanchín Formation deposition began around 6.24 ± 0.38 Ma, extending to 2.69 ± 0.38 Ma. • It was deposited as a distributary fluvial system with multiple progradational pulses. • Sediment source was mainly from North and East, where Sierras Pampeanas outcrops. • Pampean sources prevail in Guanchín Formation's upper member. • Sierras Pampeanas uplift fully partitioned the Fiambalá Basin. [ABSTRACT FROM AUTHOR]