Despite long being the target of racism, Asians and Asian Americans remain an understudied group regarding the mental health implications of racism. Even less is known about how Asians and Asian Americans may use religion to cope with racism and the resulting mental health implications. In this study, 330 Asian and Asian American adults from various regions of the USA were surveyed. The study results suggest that negative religious coping was associated with worsening depression, anxiety, and stress, particularly among Asian Indians, Asian Hindus, and Asian Muslims. In addition, negative religious coping may have exacerbated the deleterious effects of racism on mental health. Surprisingly, positive religious coping failed to provide any protection against racism-related mental health problems during the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]