1. Arterial pulse pressure amplification described by means of a nonlinear wave model: characterization of human aging
- Author
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Walter Legnani, Ricardo L. Armentano, Sandra Wray, M. R. Alfonso, Leandro J. Cymberknop, and Franco Pessana
- Subjects
Arterial pulse pressure ,History ,Materials science ,Quantitative Biology::Tissues and Organs ,Physics::Medical Physics ,Mechanics ,medicine.disease ,Computer Science Applications ,Education ,Pulse (physics) ,Pulse pressure ,Nonlinear system ,Wave model ,Blood pressure ,Arterial stiffness ,medicine ,Waveform ,Biomedical engineering - Abstract
The representation of blood pressure pulse as a combination of solitons captures many of the phenomena observed during its propagation along the systemic circulation. The aim of this work is to analyze the applicability of a compartmental model for propagation regarding the pressure pulse amplification associated with arterial aging. The model was applied to blood pressure waveforms that were synthesized using solitons, and then validated by waveforms obtained from individuals from differentiated age groups. Morphological changes were verified in the blood pressure waveform as a consequence of the aging process (i.e. due to the increase in arterial stiffness). These changes are the result of both a nonlinear interaction and the phenomena present in the propagation of nonlinear mechanic waves.
- Published
- 2016