1. Room air challenge predicts duration of supplemental respiratory support for infants with bronchopulmonary dysplasia
- Author
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Sara K Dawson, Allison Dahlgren, Puneet Arora, Jonathan Leuthner, and Joanne Lagatta
- Subjects
Pediatrics ,medicine.medical_specialty ,Time Factors ,business.industry ,Proportional hazards model ,Home oxygen ,Hazard ratio ,Postmenstrual Age ,Infant, Newborn ,Obstetrics and Gynecology ,Infant ,medicine.disease ,Respiratory support ,Article ,Bronchopulmonary dysplasia ,Pediatrics, Perinatology and Child Health ,Room air distribution ,Medicine ,Humans ,Prospective Studies ,business ,Prospective cohort study ,Infant, Premature ,Bronchopulmonary Dysplasia - Abstract
Objective: To determine whether a room air challenge (RAC) correlates with duration of respiratory support for infants with bronchopulmonary dysplasia (BPD). Study design: Prospective study of preterm infants with BPD from 2015–2018. Infants receiving ≤2 liters flow at 36 weeks post-menstrual age (PMA) underwent RAC. Cox regression was used to adjust the duration of respiratory support after 36 weeks PMA for significant covariates. Results: Of 161 infants with BPD, 91 were eligible for RAC; 51 passed and 40 failed. Infants who failed RAC had longer respiratory support after 36 weeks PMA than infants who passed (median 19 weeks (IQR 15–33) versus 2 weeks (IQR 1–8, p
- Published
- 2020