1. Acute febrile cholestatic jaundice in children: keep in mind Kawasaki disease.
- Author
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Taddio A, Pellegrin MC, Centenari C, Filippeschi IP, Ventura A, and Maggiore G
- Subjects
- Child, Child, Preschool, Diagnosis, Differential, Female, Fever etiology, Humans, Infant, Jaundice, Obstructive etiology, Male, Mucocutaneous Lymph Node Syndrome complications, Virus Diseases complications, Fever diagnosis, Jaundice, Obstructive diagnosis, Mucocutaneous Lymph Node Syndrome diagnosis
- Abstract
Kawasaki disease (KD) is characterized by persistent fever in addition to 4 of 5 signs of mucocutaneous inflammation. Although gastrointestinal involvement does not belong to the classic diagnostic criteria, it has been often associated with KD onset. We reviewed patients who were admitted for febrile cholestatic jaundice between 2003 and 2010 in 2 tertiary pediatric care centers. KD was the second most frequent cause (21%) after viral infections. Considering the relative high frequency of this condition, a high index of suspicion of KD should be maintained in patients presenting with febrile cholestatic jaundice.
- Published
- 2012
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