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Your search keyword '"Preethy, Senthilkumar"' showing total 5 results
Start Over "Preethy, Senthilkumar" Journal journal of orthopaedics
5 results on '"Preethy, Senthilkumar"'

3. Transplantation of autologous chondrocytes ex-vivo expanded using Thermoreversible Gelation Polymer in a rabbit model of articular cartilage defect

Author

Rajappa Senthilkumar, Rajeswar Chinnuswami, Karthick Ramalingam, Balasubramanyan Bhupesh Karthik, Rajmohan Mathaiyan, Yuichi Mori, Preethy Senthilkumar, Samuel J. K. Abraham, Hiroshi Yoshioka, and Sivaraman Arumugam

Subjects
030222 orthopedics, medicine.medical_specialty, Scaffold, Pathology, medicine.diagnostic_test, business.industry, Articular cartilage, In vitro, Surgery, Transplantation, 03 medical and health sciences, 0302 clinical medicine, Tissue engineering, Biopsy, medicine, Orthopedics and Sports Medicine, 030212 general & internal medicine, Autologous chondrocyte implantation, business, Ex vivo
Abstract

Graft failure due to de-differentiation of the chondrocytes during in vitro culture and after transplantation is a major hurdle in Autologous Chondrocyte Implantation (ACI). We, herein, report the transplantation of autologous chondrocytes ex vivo expanded using a Thermo-reversible Gelation Polymer (TGP) in a rabbit model. A full thickness chondral defect was created in one of the knee joints in each of the six rabbits of the study and autologous chondrocytes in vitro expanded using TGP scaffold were transplanted after 10 weeks. H & E staining of the biopsy after 6 months revealed maintenance of articular cartilage phenotype.

Published
2017

4. Transplantation of autologous chondrocytes

Author

Sivaraman, Arumugam, Balasubramanyan, Bhupesh Karthik, Rajeswar, Chinnuswami, Yuichi, Mori, Hiroshi, Yoshioka, Rajappa, Senthilkumar, Rajmohan, Mathaiyan, Karthick, Ramalingam, Preethy, Senthilkumar, and Samuel J K, Abraham

Subjects
Short Report
Abstract

Graft failure due to de-differentiation of the chondrocytes during in vitro culture and after transplantation is a major hurdle in Autologous Chondrocyte Implantation (ACI). We, herein, report the transplantation of autologous chondrocytes ex vivo expanded using a Thermo-reversible Gelation Polymer (TGP) in a rabbit model. A full thickness chondral defect was created in one of the knee joints in each of the six rabbits of the study and autologous chondrocytes in vitro expanded using TGP scaffold were transplanted after 10 weeks. H & E staining of the biopsy after 6 months revealed maintenance of articular cartilage phenotype.

Published
2016

5. Transplantation of autologous chondrocytes ex-vivo expanded using Thermoreversible Gelation Polymer in a rabbit model of articular cartilage defect.

Author

Arumugam, Sivaraman, Karthik, Balasubramanyan Bhupesh, Rajeswar, Chinnuswami, Mori, Yuichi, Yoshioka, Hiroshi, Senthilkumar, Rajappa, Rajmohan, Mathaiyan, Karthickc, Ramalingam, Preethy, Senthilkumar, and Abraham, Samuel J. K.

Subjects
CARTILAGE cell transplantation, POLYMERS, ANIMAL experimentation, ARTICULAR cartilage, BIOLOGICAL models, BIOPSY, BONE grafting, CARTILAGE cells, GRAFT rejection, RABBITS, STAINS & staining (Microscopy), ARTICULAR cartilage injuries, PHENOMENOLOGICAL biology, IN vitro studies, THERAPEUTICS
Abstract

Graft failure due to de-differentiation of the chondrocytes during in vitro culture and after transplantation is a major hurdle in Autologous Chondrocyte Implantation (ACI). We, herein, report the transplantation of autologous chondrocytes ex vivo expanded using a Thermo-reversible Gelation Polymer (TGP) in a rabbit model. A full thickness chondral defect was created in one of the knee joints in each of the six rabbits of the study and autologous chondrocytes in vitro expanded using TGP scaffold were transplanted after 10 weeks. H & E staining of the biopsy after 6 months revealed maintenance of articular cartilage phenotype. [ABSTRACT FROM AUTHOR]

Published
2017
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