1. Antibiotic Cement-Coated Interlocked Intramedullary Nails for the Treatment of Infected Nonunion After Intramedullary Nailing
- Author
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Abdul K, Zalikha, Zain, Sayeed, Sasha A, Stine, Ryan, Bray, and Rahul, Vaidya
- Subjects
Fracture Healing ,Treatment Outcome ,Fractures, Ununited ,Bone Cements ,Humans ,Orthopedics and Sports Medicine ,Surgery ,General Medicine ,Bone Nails ,Fracture Fixation, Intramedullary ,Retrospective Studies ,Anti-Bacterial Agents - Abstract
To evaluate outcomes using an interlocking antibiotic cement-coated nail and culture-specific systematic antibiotics in the treatment of infected nonunion after intramedullary nailing.Retrospective observational cohort study.Urban level I trauma center.Forty-one nonconsecutive patients who presented to a level I trauma center who underwent interlocked antibiotic nailing for treatment of infected nonunion status after primary intramedullary nailing.Eradication of infection, radiographic union by 2-year follow-up.Antibiotic nailing successfully eradicated infection and led to fracture healing in 35 patients (85.4%), while 6 patients (14.6%) had persistent infection and required further surgical treatment. Of the 6 patients who required further treatment, 5 eventually went on to heal with fracture union and eradication of their infection, while 1 required a salvage procedure. Of the 5 patients who eventually went on to heal, 4 of them healed with repeat antibiotic or intramedullary nails, while 1 required segmental resection and bone grafting before healing.This study suggests that the proposed interlocked antibiotic nailing technique is a viable therapeutic option to eradicate infected nonunion and support fracture healing.Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
- Published
- 2023