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Start Over Author "Shi-Sheng Wang" Journal journal of organic chemistry
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1. Oxidative Radical Addition/Cyclization Cascade for the Construction of Carbonyl-Containing Quinoline-2,4(1H,3H)-Diones.

Author

Shi-Sheng Wang, Hong Fu, Yuehai Shen, Meng Sun, and Ya-Min Li

Subjects
*OXIDATIVE addition, *RING formation (Chemistry), *CARBONYL compounds, *QUINOLINE, *ALDEHYDES, *FUNCTIONAL groups
Abstract

Oxidative radical addition/cyclization cascade of o-cyanoarylacrylamides with a-keto acids as well as aldehydes is reported. This transformation exhibits a wide substrate scope and significant functional group tolerance and provides a convenient and highly efficient access to carbonyl-containing quinoline-2,4(1H,3H)-diones. A possible mechanism for the transformation is proposed. [ABSTRACT FROM AUTHOR]

Published
2016
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