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Your search keyword '"MÉTAY, E."' showing total 2 results
Start Over Author "MÉTAY, E." Journal journal of organic chemistry
2 results on '"MÉTAY, E."'

1. Solvent-free Michael addition to non-protected 3-(2-nitrovinyl)indole by ultrasound activation.

Author

Baron M, Métay E, Lemaire M, and Popowycz F

Abstract

A variety of nucleophiles provided by activated methylenes have been added on 3-(2-nitrovinyl)-1H-indole in very good to excellent yields, under sonication and solvent-free conditions, using solid potassium carbonate or sodium acetate as a base. Direct synthesis avoiding preliminary NH protection is reported and exemplified to 15 molecules.

Published
2012
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2. Synthesis of 3-aryl-8-oxo-5,6,7,8-tetrahydroindolizines via a palladium-catalyzed arylation and heteroarylation.

Author

Gracia S, Cazorla C, Métay E, Pellet-Rostaing S, and Lemaire M

Subjects
Catalysis, Heterocyclic Compounds chemistry, Magnetic Resonance Spectroscopy, Models, Molecular, Molecular Structure, Structure-Activity Relationship, Heterocyclic Compounds chemical synthesis, Indolizines chemical synthesis, Palladium chemistry
Abstract

A selective palladium-catalyzed arylation and heteroarylation of 8-oxo-5,6,7,8-tetrahydroindolizines has been developed. Mechanistic studies assume an electrophilic substitution pathway for this transformation. This method provides an efficient one-step synthesis of 3-aryl-8-oxo-5,6,7,8-tetrahydroindolizines.

Published
2009
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