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1. Synthesis of Polycyclic Isoindoline Derivatives via Tandem Pd-Catalyzed Coupling, Propargyl--llenyl Isomerization, [4 + 2] Cycloaddition and Aromatization Reaction.

Author

Shugao Zhu, Jian Cao, Luling Wu, and Xian Huang

Subjects
*ISOMERIZATION, *CHEMICAL synthesis, *INDOLINE, *SONOGASHIRA reaction, *RING formation (Chemistry), *AROMATIZATION
Abstract

We report in this paper an interesting sequential reaction involving sequential Sonogashira coupling, propargyl-allenyl isomerization, [4 + 2] cycloaddition and aromatization reaction, which provides a facile method for the synthesis of a variety of polycyclic isoindoline derivatives from easily accessible starting materials. [ABSTRACT FROM AUTHOR]

Published
2012
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