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Start Over Author "Vilia Elena Spiegel-Ciobanu" Journal journal of occupational and environmental medicine
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1. Relationship between welding fume concentration and systemic inflammation after controlled exposure of human subjects with welding fumes from metal inert gas brazing of zinc-coated materials

Author

Thomas Kraus, Monika Gube, Marcus Bauer, Klaus Lenz, Uwe Reisgen, Vilia Elena Spiegel-Ciobanu, and Peter Brand

Subjects
Male, Materials science, chemistry.chemical_element, Zinc, Welding, Welding fume, Systemic inflammation, medicine.disease_cause, law.invention, Metal, law, medicine, Brazing, Humans, Inert gas, Inflammation, Inhalation Exposure, No-Observed-Adverse-Effect Level, Metallurgy, Public Health, Environmental and Occupational Health, C-Reactive Protein, chemistry, visual_art, Zinc toxicity, visual_art.visual_art_medium, Gases, medicine.symptom
Abstract

It has been shown that exposure of subjects to emissions from a metal inert gas (MIG) brazing process of zinc-coated material led to an increase of high-sensitivity C-reactive protein (hsCRP) in the blood. In this study, the no-observed-effect level (NOEL) for such emissions was assessed.Twelve healthy subjects were exposed for 6 hours to different concentrations of MIG brazing fumes under controlled conditions. High-sensitivity C-reactive protein was measured in the blood.For welding fumes containing 1.20 and 1.50 mg m zinc, high-sensitivity C-reactive protein was increased the day after exposure. For 0.90 mg m zinc, no increase was detected.These data indicate that the no-observed-effect level for emissions from a MIG brazing process of zinc-coated material in respect to systemic inflammation is found for welding fumes with zinc concentrations between 0.90 and 1.20 mg m.

Published
2013

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