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Introduction Cavernous malformations localized in the brain stem are considered as a separate entity in relation to other intracranial cavernoma. Clinical presentation is specific in terms of focal neurologic deficit; they show aggressive biological behavior and unfavorable clinical course, whereas localization in the brain stem naturally represents the largest surgical problem and challenge and significantly higher operational risk. Results We report a series of 10 patients with brainstem cavernoma, operated at the Department of Neurosurgery, Clinical Center of Serbia, between 2008 and 2012. In cavernous lesions of the dorsal pons and upper cerebellar peduncle, we used the approach through the fourth ventricle; in the laterally localized pontine cavernoma, we used the cerebellopontine angle approach, and in the cavernoma localized in the central midbrain tegmental area, we used the supracerebellar infratentorial approach. Conclusion Surgical removal of the brainstem cavernoma is absolutely expedient both from the standpoint of preventing recurrent and debilitating hemorrhage and in terms of recovery of neurologic deficit. In patients with disturbed vital functions, the evacuation of the hematoma and removal of the malformation eliminate compression of effects on vital structures of the brain stem. Keywords brain stem; cavernomas; approach

Introduction Natural course of aneurysms that occur on blood vessels of the brain singles out the need for understanding the mechanism of the occurrence of aneurysm wall rupture and identification of anatomic characteristics as predictive factors for hemorrhage to occur. Aim In this study, we comparatively present results of our researches and experimental models on animals. Material and Methods We made a comparative analysis of anatomical characteristics of blood vessels of the brain and aneurysms obtained on the basis of digital subtraction angiography and intraoperative finding. In this article, we review recent research in the anatomic characteristics of intracranial aneurysms and parent blood vessels. Results We present a series of 185 aneurysms (ruptured and unruptured) dissected at the Neurosurgical Clinic of Clinical Center of Serbia in Belgrade. Inclination angle may be considered as the vital predisposing factor for intracranial aneurysm rupture. In aneurysms that ruptured, it was 139.748 ± 27.242 degrees, while in unruptured aneurysms it was considerably smaller and amounted to 100.882 ± 22.001 degrees (p