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Your search keyword '"Brito RN"' showing total 2 results
Start Over Author "Brito RN" Journal journal of neuroimmunology
2 results on '"Brito RN"'

1. Balneotherapy decreases mechanical hyperalgesia by reversing BDNF and NOS2 immunocontent in spinal cord of mice with neuropathic pain.

Author

de Brito RN, Ludtke DD, de Oliveira BH, de Oliveira Galassi T, Fernandes PF, Van Den Berge S, Salgado ASI, Cidral-Filho FJ, Horewicz VV, Bobinski F, and Martins DF

Subjects
Animals, Male, Mice, Balneology methods, Brain-Derived Neurotrophic Factor metabolism, Hyperalgesia metabolism, Neuralgia, Nitric Oxide Synthase Type II metabolism, Spinal Cord metabolism
Abstract

In the last decades, balneotherapy or thermalism has been used for health promotion and in the treatment of inflammatory and chronic processes. We found that balneotherapy reduced mechanical hyperalgesia, as well the increase of BDNF and NOS2 levels in the spinal cord, while increased BDNF and NOS1 in the paw. The data presented herein demonstrated for the first time in a murine model of neuropathic pain, the analgesic effect of balneotherapy with the water from the natural springs of Santo Amaro da Imperatriz-Brazil. Nevertheless, future clinical trials should be conducted to test the effectiveness of balneotherapy in neuropathic pain patients., Competing Interests: Declaration of Competing Interest The authors declare that they have no conflict of interest., (Copyright © 2020 Elsevier B.V. All rights reserved.)

Published
2020
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2. Aquatic exercise and Far Infrared (FIR) modulates pain and blood cytokines in fibromyalgia patients: A double-blind, randomized, placebo-controlled pilot study.

Author

Salm DC, Belmonte LAO, Emer AA, Leonel LDS, de Brito RN, da Rocha CC, Martins TC, Dos Reis DC, Moro ARP, Mazzardo-Martins L, Kviecinski MR, Bobinski F, Salgado ASI, Cidral-Filho FJ, and Martins DF

Subjects
Adult, Aged, Biomarkers blood, Ceramics, Double-Blind Method, Exercise psychology, Female, Fibromyalgia psychology, Humans, Male, Middle Aged, Pain blood, Pain psychology, Pilot Projects, Quality of Life psychology, Swimming Pools, Cytokines blood, Exercise physiology, Fibromyalgia blood, Fibromyalgia therapy, Infrared Rays therapeutic use, Pain Management methods
Abstract

Fibromyalgia (FM) has an inflammatory component, as elevated serum levels of inflammatory biomarkers are associated with its diagnosis. Treatments decreased pain, body temperature, improved quality of life and reduced serum levels of IL-6 in both groups; however, these beneficial effects were more pronounced in aquatic exercise (AE) + Far-Infrared (FIR) group. The findings of the present study suggest that the association of AE to FIR increases the benefits of aquatic exercise in patients with FM., (Copyright © 2019 Elsevier B.V. All rights reserved.)

Published
2019
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