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Xia Wang, Yanhua Liu Department of Nursing, Tianjin Beichen Traditional Chinese Medicine Hospital, Tianjin, 300400, People’s Republic of ChinaCorrespondence: Yanhua Liu, Email Liuyh1017@126.comBackground: Although the “ 6S” management was shown to improve the work efficiency and quality of enterprises, the significance of lean “ 6S” combined with visual management in clinical nursing settings has not yet been reported.Objective: This study aimed to explore the effect of lean “ 6S” combined with visual management mode on clinical nursing quality.Methods: From June 2019, the “ 6S” combined with visual management mode was implemented in Tianjin Beichen Traditional Chinese Medicine Hospital. The satisfaction of nurses in the ward, hand-over items and warehouse inventory time, ICU rescue efficiency, and the incidence of nursing adverse events before and after the implementation of the mode were compared.Results: Implementation of the visual and “ 6S” management mode led to significantly higher satisfaction of nurses in the ward compared to pre-implementation. Further, a significant decrease was observed in hand-over items and warehouse inventory time, ICU rescue efficiency, and the incidence of adverse nursing events (P< 0.05).Conclusion: The visual and “ 6S” management mode in the ward could significantly improve the quality of clinical nursing management and the satisfaction of medical staffs. This study is a single-centre prospective study, so some selection bias is inevitable. Future multicentre, long-term randomized clinical trials are needed to provide more evidence that this method can benefit nursing practice.Keywords: “ 6S” management, visual management, nursing, intensive care unit, rescue, safety, inventory time, satisfaction