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Objective To investigate the current status and related factors of clinicians in implementing blood transfusion notification obligations, in order to provide scientific basis for the formulation of measures to improve the quality of implementing the blood transfusion notification obligation.Methods Using the method of prevalence survey, a total of 144 clinicians who had received at least one red blood cell transfusion order from April 1 to June 30,2019 in a tertiary hospital were taken as the research objects, and the revised questionnaire about clinicians′ notification obligation of blood transfusion in British blood transfusion review was used as the survey tool, which mainly included the general situation of the research objects and the implementation of the notification obligations of 15 core blood transfusion items.The SPSS23.0 software was used for statistical analysis.Results 73.61%（106/144） clinicians had the time of implementing the notification of blood transfusion more than five minutes, which could effectively answer 75.00%（108/144） patients′ questions.There were significant differences in the proportion of clinicians′implementation of notification obligations of the blood transfusion items, among which 34.72%（50/144） clinicians had poor implementation of blood transfusion notification obligation（entries score less than 10 points）.The department, age, gender, professional and technical position, and working years had nothing to do with clinicians′ notification obligation of blood transfusion, and the differences were not statistically significant（P>0.05）.However, receiving transfusion training in clinical practice was an independent factor affecting the quality of transfusion notification obligation（OR=4.72,95%CI:1.71-13.02,P=0.003）.When implementing the obligation of notification, clinicians rarely notifed the relatively rare blood transfusion methods or infrequent transfusion risks, and did not fully notify the alternative treatment plan of blood transfusion.More than half of clinicians did not notify the patients that they could not donate blood within one year after transfusion.Conclusion The quality of clinicians′ implementing part of the notification obligation blood transfusion needs to be improved.Targeted systematic training is conducive to improving the quality of clinicians′ implementation of the notification obligation blood transfusion, so that patients can actively participate in blood transfusion decision-making, so as to improve the quality and safety of blood transfusion. [ABSTRACT FROM AUTHOR]

Objective To compare the space-time parameters characteristics of different ages of healthy people and elderly patients with knee osteoarthritis by the gait analysis in order to provide a new scientific basis for the clinical diagnosis of early elderly patients with knee osteoarthritis. Methods Twenty patients with bilateral knee osteoarthritis hospitalized in the orthopedic department of this hospital from January to June 2021 were selected,20 healthy elderly subjects and 20 healthy young subjects were collected from the outpatient department. All 60 subjects conducted the gait analytical test. The subjects were divided into three groups:the young control group,elderly control group and elderly knee osteoarthritis group. Results Compared with the elderly control group and young control group,the walking speed and stride frequency in the elderly knee osteoarthritis group were slower,the stride length was shorter,the gait cycle was longer,and the double support phase was increased (P <0. 05); compared with the young control group,the walking speed, stride length,gait period and double support phase in the elderly control group had no significant changes(P > 0. 05). Seeing Table 2. The step length bias had no statistically significant differences among 3 groups (P > 0. 05). Conclusion The gait of elderly patients with knee osteoarthritis is characterized by slow walking speed,low stride frequency,short stride length,long gait cycle and long dual support phase [ABSTRACT FROM AUTHOR]

Objective To analyze and understand the epidemic situation and trend of HIV/AIDS in Changshou District of Chongqing,and to provide reference for the formulation of HIV/AIDS prevention and control measures. Methods The basic information system of HIV/AIDS prevention and control in disease prevention and control information system of China was used to download the epidemic data of HIV/AIDS new cases in Changshou District from 2003 to 2017 according to the current address, established a database and conduct descriptive epidemiological studies. Results 1 160 HIV/AIDS cases were reported in Changshou District from 2003 to 2017, of which 221 died, and the number of new cases was increasing year by year. Of the cases reported, 912 males accounted for 78.6%.People aged 15-<50 accounted for 69.5% of the total, and the proportion of people aged 50 and over were increasing year by year, reached 56.1%in 2017.Among the transmission channels, heterosexual transmission accounted for 68.1%,and its proportion was increasing year by year. The population classification was highest in retirement, household/unemployed people and farmers,29.7%and 28.0%respectively, and the proportion of cases classified as "unknown" was 11.6%. Statistics by sample source,the passive detection of other diseases in hospital or preoperative detection accounted for 43.1%. Secondly, 28.3% and 19.9% of the cases were reported by examination and consultation,detention or re-education through labor or physical examination of drug addicts. Conclusion The newly discovered cases of HIV/AIDS in Changshou District have increased year by year, mainly sexual transmission, and the proportion of males is higher than that of females, the proportion of people aged 50 and over in newly discovered cases has increased year by year. Intervention and testing of high-risk groups should be strengthened, publicity and education on AIDS knowledge for people aged 50 and over should be carried out, and the construction of voluntary counseling and testing clinics for AIDS should be strengthened to slow down and control the epidemic of AIDS. [ABSTRACT FROM AUTHOR]

Objective To investigat the distribution and drug resistance of Klebsiella pneumoniae in urinary tract infec⁃ tion of the hospital，and provide a reliable basis for the diagnosis and treatment of urinary tract infection. Methods 510 urine culture specimens of UTIs patients admitted to the hospital from January 1，2007 to December 31，2016 were collected. Routine methods were used to isolate bacteria which were identified and tested for minimum in hibitory concentration by VITEK 2 Compact automatic bacteria analyzer. κ⁃B disk diffusion method as a supplement，and the results were judged according to CLSI standard. Results The isolating rate of Klebsiella pneumoniae was highest in nephrology department for 18.4%（94/510）；the resistance rates of Cephalosporins were all above 39.0%，that of Piperacillin/Tazobactam and Cefoperazole/Sulbactam were lower than 39.0%，that of Amikacin，Imipenem and Meropenem were lower than 22.0%；CRE isolating rate was rising. Conclusion Klebsiella pneumoniae is an important pathogen of nosocomial infection，whose isolatingand drug resistance rate are increasing. Paying great attention，strengthening the monitoring，nursing and infection control，as well as using antibiotic rationally are essential. [ABSTRACT FROM AUTHOR]

目的 建立北京市密云区1~3d新生儿血清敏肌钙蛋白I(hsTnI)的参考区间。方法 回顾 性选取2020-2021该院分娩筛查的新生儿257例,采用 BECKMANDxI800免疫分析仪对血清hsTnI进行检 测并建立参考区间。结果 1~3d新生儿血清hsTnI水平依次为21.60(12.60,30.60)、19.88(9.12,30.63)、 24.96(15.60,34.32)pg/mL,差异无统计学意义(P>0.05)。不同日龄新生儿中,不同性别新生儿血清hsTnI 水平比较,差异无统计学意义(P>0.05)。1~3d新生儿血清hsTnI水平参考区间为7~48pg/mL,并通过验 证。结论 该地区1~3d新生儿血清hsTnI水平参考区间可设定为7~48pg/mL. [ABSTRACT FROM AUTHOR]

Objective: To analyze the factors affecting the self care ability of the patients with acute mushroom poisoning, and to compare the differences of clinical indexes and prognosis between the patients with unable self care and the patients with basic self care. Methods: A total of 184 cases of acute mushroom poisoning treated in the Affiliated Hospital of Southwest Medical University from March 2017 to November 2018 were selected. The clinical data and the scores in each item of Barthel index were collected. The cases were divided into the unable self care group (c:(60 points, 63 cases) and basic self care group (> 60 points,121 cases) according to the total score value. The differences in the clinical indicators and prognosis were analyzed and compared between the two groups by using the multivariate logistic regression model. Results: The sex, age, hospitalization time, platelet (Plt), hemoglobin(Hb), creatinine, albumin, bilirubin and proportion of complicating liver failure had no statistical differences between the two groups(P > 0.05). Compared with the basic self care group, the levels of glutamic transaminase (ALT ), glutamic oxalacetic transaminase (AST), prothrombin activily(PTA), activated partial thromboplastin time (APTT), white blood cells count, red blood cells count, urea and proportion of complicating renal failure in the unable self care group were higher, and the differences were statistically significant (P<0.05). Among 184 cases, 8 cases died with the mortality rate of 4. 35% and all death cases occurred in the unable self care group, the mortality rate had statistical difference between the two groups (P < 0.05). The higher the PT A and RBC, the lower the risk of unable self care (P< 0.05), the higher the urea level, the higher the risk of unable self care (P< 0. 05). Conclusion: The patients with acute mushroom poisoning and unable self care should adopted the pertinent nursing measures, recover their living self care ability to the utmost extent, reduce the occurrence rate of complications and increase the survival rate. [ABSTRACT FROM AUTHOR]

Objective To understand the pathogen spectrum and the change of drug resistance rate of urinary tract infection in a hospital from 2008 to 2017, and provide evidence for clinical diagnosis and treatment. Methods Retrospective analysis was carried out to study the pathogens and drug resistance rate of urinary tract infection from January 2008 to December 2017 in a hospital. Data analysis was performed using WHONET5. 6 software and SPSS17. 0. Results There was no significant change in the pathogen spectrum of urinary tract infection in the past 10 years. Escherichia coli was still the main pathogen, followed by Enterococcus faecium, Klebsiella pneumoniae and Enterococcus faecalis. The fungus was mainly isolated from Candida albicans and Candida tropicalis. The resistance rates of Klebsiella pneumoniae and Escherichia coli to the second, third and fourth generation cephalosporins and aminoglycoside antibiotics were similar, and there was no significant change in 10 years. The resistance rate of Klebsiella pneumoniae to enzyme-containing inhibitors was higher than that of Escherichia coli. The resistance rate of Escherichia coli to quinolones was significantly higher than that of Klebsiella pneumoniae. The resistance rate of Klebsiella pneumoniae to carbapenems increased year by year and was significantly higher than Escherichia coli. The resistance rate of Enterococcus faecium to ampicillin, erythromycin and quinolones was over 90%, and there was no significant change in 10 years. Enterococcus faecium still had high sensitivity to vancomycin, linezolid and teicoplanin. Conclusion There is no significant change in the pathogen spectrum of urinary tract infection in the past 10 years. Carbapenem-resistant Enterobacteriaceae bacteria, enterococci resistant to vancomycin, teicoplanin and linezolid need to be paid attention to. The distribution characteristics of the clinical departments of the above bacteria and the risk factors of susceptible patients should be understood. Individualized treatment options are developed based on the patient′s own condition to curb the spread and prevalence of resistant bacteria. [ABSTRACT FROM AUTHOR]

目的分析改良T 氏穿刺结合椎间孔镜270°神经根减压治疗腰椎管狭窄症的临床疗效。方法选取 2014-2016 年在该科进行改良T 氏穿刺结合椎间孔镜270°神经根减压治疗的108 例腰椎管狭窄症患者作为研究 对象，采用视觉疼痛模拟量表（VAS）评分和Oswestry 残疾指数（ODI）评分评价患者疼痛及腰部功能，采用Nakai 评分 标准评价临床疗效。结果108 例腰椎管狭窄症患者手术优良率为79.63%（86/108）；术后各时间点的VAS、ODI 评分均 较术前显著降低，差异均有统计学意义（P<0.05），且术后VAS、ODI 评分在各时间点比较，差异均有统计学意义（F=492.61、 189.92，P=0.000、0.006）。结论改良T 氏穿刺结合椎间孔镜270°神经根减压治疗腰椎管狭窄症的临床疗效较好。 [ABSTRACT FROM AUTHOR]