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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the effect of early fluid resuscitation on systemic inflammatory response in patients with severe acute pancreatitis (SAP). Methods The 44 SAP patients admitted to the ICU of the hospital from May 2016 to May 2019 were subjected to restrictive volume resuscitation, continuous blood purification, somatostatin and gabexate inhibit pancreatic secretion, inhibit acid, prevent infection, and control Standard treatments such as blood sugar, correction of internal environment disorders, and traditional Chinese medicine enemac Observing the patient's total fluid balance within 72 hours of treatment, lactic acid level, abdominal pressure, oxygenation index, interleukin-6(IL-6)and tumor necrosis factor-α (TNF-α) levels, and symptom relief after 72 hours. Results Fluid balance within 72 hours was negatively correlated with oxygenation index after treatment (P <0. 05), and positively correlated with abdominal pressure, IL-6 and TNF- αlevels (P <0. 05), fluid balance within 72 hours was an early symptom Relevant factors can be alleviated (P <0. 05). Conclusion In the early treatment of SAP patients, the use of fluid resuscitation to reduce the positive fluid balance can reduce the patient's systemic inflammatory response. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

新型冠状病毒肺炎(以下简称"新冠肺炎”)瘦情期间,采取安全管理措施,全方位保护医护和患者安全,可有效避 免新冠肺炎感染的发生。依赖于完善的制度、唷力的监督、有效的防护及各方人员的积极配合,该院妇产科全体医护人员、妇产科 惠者及家属、所有新生儿均未出现感染。 [ABSTRACT FROM AUTHOR]

目的探讨集束化护理模式在腹腔镜胃癌根治术患者中的应用效果。方法选取2018年9月至2019年9月该院行腹腔镜胃癌根治术的患者96例，随机分为观察组和对照组，每组48例。对照组采用常规护理模式，观察组在对照组基础上采用集束化护理模式，比较两组术后肠鸣音恢复时间、首次排气时间、首次排便时间、胃管留置时间、生活质量评分、不良反应发生率及护理满意度。结果观察组术后肠鸣音恢复时间、首次排气时间、首次排便时间及胃管留置时间均少于对照组，差异均有统计学意义（P＜0.05）。观察组生理职能、躯体疼痛、精神健康及活力评分均高于对照组，差异均有统计学意义（P＜0.05）。观察组不良反应总发生率及护理总满意度均优于对照组，差异有统计学意义（P＜0.05）。结论将集束化护理模式应用于腹腔镜胃癌根治术患者护理中，有利于实现护理质量的持续改进，促进患者术后胃肠功能的恢复，改善患者的生活质量，减少术后不良反应的发生，建立和谐的护患关系，值得临床推广应用。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To preliminarily screen the enzyme protein with large influence on the metabolism level of Homoeysteinemia (Hey) and investigate the eorrelation between Hey and eoronary heart disease ( CHD ) at gene level. Methods Two hundred and sixty cases of CHD met the eriteria(the CHD group) and 300 cases of physical exmination (the eon- trol group) in our hospital from September 2013 to June 2014 were enrolled in this study. The blood levels of Hey and related bio- ehemieal indieators were deteeted,and the methylenyltetrahydrofolate redutase(MTHFR) C677T gene polymorphism was detect­ed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results The plasma Hey level of the CHD group was (19.3±7.2) pmol/L，whieh was signifieantly higher than that in the eontrol group (15.1 ±4.9)pmol/L(P<0.05); The differenee in three gene types of CC，CT and TT between the CHD group and the eontrol group was statistieally signifieant (P<0.05)，and the differenee of Hey eoneentration in the plasma of the three genotypes was statistically significant (P<0.01). Conclusion The gene polymorphism of MTHFR C677T in northeast Siehuan area is assoeiated with the elevation of plasma Hey levels，suggesting that it may be a risk faetor for eoronary heart disease. [ABSTRACT FROM AUTHOR]

以临床药师的角度分析围手术期高血压药物术前规范处置与术后发生并发症的相关性、血压 异常后药物选择合理性,以期降低术后并发症的发生风险及病死率。目前,关于合并高血压住院患者术前是否 应该停药及如何停药尚未达成定论。制定住院患者高血压药物术前规范处置管理的专家共识,以及围手术期 发生血压异常后药物选择的适宜性势在必行。 [ABSTRACT FROM AUTHOR]

Objective To prepare the sinomenine long circulating liposomes to prolong the action time of the drug，reduce the toxicity and enhance the targeted therapeutic effects for tumor treatment. Methods With the entrapment rate as the index，the orthogonal design was adopted to optimize the ratio of drug to lipid，the ratio of cholesterol to lipid，PEG 6000 content and ultrasonic time. Results The optimized technology was as follows: the ratio of drug to lipid was 1∶8，the ratio of cholesterol to lipid was 1∶3，the PEG 6000 content was 0.25%，and the ultrasonic time was 15 min. The three batches of validation tests were conducted according to this technology. The detected entrapment rates were 61.25%，60.17% and 62.33% respectively. Conclusion The method has the advantages of stable technology，simple preparation method and good repeatability，so it is suitable for the preparation of sinomenine long circulating liposomes. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨一体化教学模式在麻醉学本科专业临床麻醉教学中的应用效果，构建信息化的教学模式，以 提高教学质量。方法选取该校2011级麻醉学本科专业学生60名，将其随机分为一体化教学组和传统教学组，各30例。 分别采用一体化教学模式和传统教学模式授课，分两个阶段通过理论考试、技能考核来评价两种教学模式的教学效果。 结果一体化教学组的教学效果明显优于传统教学组，差异均有统计学意义（P<0.05);在学习效果评价方面，相对于传 统教学组，一体化教学组中80.0%及以上的学生认为一体化教学模式激发了学习兴趣，培养了分析问题、解决问题的能 力及团队协作能力，锻炼了应变能力，提高了学习效率，差异有统计学意义(P<0.05)。结论一体化教学模式的教学效果 优于传统教学模式，能够提高临床麻醉学专业学生的培养质量。 [ABSTRACT FROM AUTHOR]