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The effect of tannic acid (TA) on the deposition of osmium was studied in discs of hamster skin and in fixed gelatin. Pieces of skin treated with 1.0% TA before OsO4 fixation absorbed almost twice as much as untreated pieces. Gelatin, used here as a model 'tissue' showed an even greater degree of enhancement. Treated gelatin capsule halves and strips took up 4-6 times as much osmium as untreated ones. The deposition of osmium was verified by neutron activation analysis.