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To assess the consciousness about informed consent (IC) of the researchers, a study was conducted in a postgraduate institute in Dhaka, Bangladesh from Dec' 2003 to Jan' 2004. A total of 39 researchers responded properly. All subjects were doctors who have completed a research work previously. A written questionnaire was given to the respondents to answer the questions about IC and then it was collected properly with the answer of the participants. The data was analyzed statistically. Most of the respondents 84.60% agreed that IC is a written consent and 94.90% respondents agreed that it includes risk and benefit. Maximum participants (97.40%) agreed that child's consent is not valid for a study, 89.70 % researchers agreed that confidentiality should be included in IC and 76.90% agreed that IC should include the duration of the study. 71.60% respondents agreed to give autonomy to the subject, 48.70% disagreed that the witness is necessary during taking IC, 66.70% respondents took IC from the study subjects during their study & 33.30 % had not taken any consent. From the present study, it can be concluded that most of the researchers of the concerned institute are knowledgeable about IC but many of them has no attitude to apply it in practice. As there is evidence of negligence to practice on IC during conducting research, awareness should be grown up amongst the researchers by conducting seminar, symposium and workshop to protect human rights during clinical trial. Â DOI = 10.3329/jom.v7i2.1363 J MEDICINE 2006; 7 : 46-50 Â

This prospective experimental study was done in the Department of Physical Medicine and Rehabilitation, Bangabandhu Sheikh Mujib Medical Universiry, Dhaka from 1st January 2008 to 31st July 2008 to observe the effects of ADL instructions on patients with osteoarthritis of the knee. A total of 60 patients with OA – knee were selected. Out of 60 patients 28(46.7%) were female and 32(53.3%) were male. The female to male ratio1.14:1. Age distribution varied from >40 years to

Pain complaints are a leading reason for medical visits.1 The most common pain complaints are musculoskeletal and LBP. The prevalence and impact of back pain have led to an expanding array of tests and treatments, including injections, surgical procedures, implantable devices, and medications. Each is valuable for some patients, but use may be expanding beyond scientifically validated indications, driven by professional concern, patient advocacy, marketing, and the media. 2-4

A total of 106 patients of osteoarthritis of knee were selected for the study. Out of 106 patients 26.41% were male and 73.58% were female. The female and male ratio is 2.78: 1. Mean age was 49.68 ± 9.16 years and house wives were maximum in number 75 (70.8%). They were divided into two groups, 52 patients in group–A, were treated with NSAID plus Exercise and another 54 patients in group-B, were treated with NSAID only. In both group patients were treated for six weeks duration. The improvement was assessed with WOMAC scoring system. Student’s‘t’ test was to see the level of significance. In present study, the patients groups those who received NSAID plus Exercise, improved more significantly (p= 0.001) than those who received NSAID only. So it can be concluded that quadriceps muscle strengthening exercise is effective in the patients with OA knee. Keyword: Osteoarthritis, Knee, Exercise. DOI: http://dx.doi.org/10.3329/jom.v12i2.8418 JOM 2011; 12(2): 120-124