6 results on '"Walton, Michael"'
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2. Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)
3. Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles as Selective, Orally Bioavailable CHK1 Inhibitors
4. Structure-Guided Evolution of Potent and Selective CHK1 Inhibitors through Scaffold Morphing
5. Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening
6. Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitrilesas Selective, Orally Bioavailable CHK1 Inhibitors.
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