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Your search keyword '"Walton, Michael"' showing total 6 results

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6 results on '"Walton, Michael"'

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1. Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease

2. Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)

3. Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles as Selective, Orally Bioavailable CHK1 Inhibitors

4. Structure-Guided Evolution of Potent and Selective CHK1 Inhibitors through Scaffold Morphing

5. Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening

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