Brucellosis is an infection that affects mammals’ cells caused by a species from the genus Brucella, a gram-negative, immobile, facultative, intracellular, and microaerophilic coccobacillus. In humans, the pathogen species are Brucella melitensis, B. abortus, B. suis and B. canis. We are presenting the case of a 62-year-old man with confirmed brucellosis and his consequent cardiovascular, cutaneous, gastrointestinal, hepatic, osteomuscular, renal and hematological complications. It is necessary to be highly suspicious of this infection, since its non-specific nature can be challenging for the physician.