1. Proton Resonance Frequency Shift Thermometry: A Review of Modern Clinical Practices
- Author
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Marcin J. Kraśny, Keyoumars Ashkan, Aoife O'Brien, James Blackwell, Josette Galligan, Niall Colgan, Michel Destrade, European Regional Development Fund, Enterprise Ireland, Irish Research Council, and College of Science, National University of Ireland, Galway
- Subjects
Male ,Mr thermometry ,TUMOR ABLATION ,Thermal ablation ,Thermal therapy ,Thermometry ,Focused ultrasound ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,INTERSTITIAL THERMAL THERAPY ,medicine ,Humans ,SUSCEPTIBILITY CHANGES ,Radiology, Nuclear Medicine and imaging ,ESSENTIAL TREMOR ,BONE METASTASES ,Proton resonance frequency ,medicine.diagnostic_test ,business.industry ,Prostate ,GUIDED LASER-ABLATION ,Magnetic resonance imaging ,MR-THERMOMETRY ,Gold standard (test) ,Magnetic Resonance Imaging ,PROSTATE-CANCER ,CHEMICAL-SHIFT ,High-Intensity Focused Ultrasound Ablation ,Tissue type ,INTENSITY-FOCUSED ULTRASOUND ,Protons ,business ,Biomedical engineering - Abstract
Magnetic resonance imaging (MRI) has become a popular modality in guiding minimally invasive thermal therapies, due to its advanced, nonionizing, imaging capabilities and its ability to record changes in temperature. A variety of MR thermometry techniques have been developed over the years, and proton resonance frequency (PRF) shift thermometry is the current clinical gold standard to treat a variety of cancers. It is used extensively to guide hyperthermic thermal ablation techniques such as high-intensity focused ultrasound (HIFU) and laser-induced thermal therapy (LITT). Essential attributes of PRF shift thermometry include excellent linearity with temperature, good sensitivity, and independence from tissue type. This noninvasive temperature mapping method gives accurate quantitative measures of the temperature evolution inside biological tissues. In this review, the current status and new developments in the fields of MR-guided HIFU and LITT are presented with an emphasis on breast, prostate, bone, uterine, and brain treatments.Level of Evidence 5Technical Efficacy Stage 3 The project was co-financed by the European Regional Development Fund (ERDF) under Ireland’s European Structural, Investment Funds Programme 2014–2020 and Enterprise Ireland; Grant agreement: CF-2017-0826-P, Irish Research Council postgraduate scholarship GOIPG/2018/82 and the NUI Galway College of Science. peer-reviewed 2021-11-20
- Published
- 2020
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