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Objective: To investigate the effect of growth hormone (GH) supplementation on the clinical outcomes in non-diminished ovarian reserve(DOR) patients with previous in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) failure. Methods: It was a retrospective, self-controlled study. The clinical outcomes of the first and se cond IVF/ICSI cycle in 174 non-DOR patients undergoing the second IVF/ICSI cycle with GH supplement, from January 1st, 2018 to December 31st, 2021 in our center, were analyzed. Results: The gonadotropin(Gn) dosage per day, number of oocytes retrieved, 2PN cleavage rate, high-quality embryo rate, embryo implantation rate and clinical pregnancy rate were significantly increased, and Gn duration were significantly decreased in the GH group compared with control group(P＜0.05). The clinical pregnancy rate was not affected by the ovarian stimulation protocol, while the differences of Gn dosage, endometrial thickness, fertilization rate and abortion rate were not statistically significant (all P＞0.05). Subgroup analysis indicated that the antral follicle count (AFC), clinical pregnancy rate and live birth rate in the ＜35 years group were higher than those in the ≥35 years group (all P＜0.05)，while there were no significant differences in body mass index (BMI), anti-mullerian hormone (AMH), basic follicle stimulating hormone(FSH), Gn duration and dosage, endometrial thickness on the day of embryo transfer, number of oocytes retrieved, fertilization rate, 2PN cleavage rate, high -quality embryo rate, embryo implantation rate and abortion rate between the two groups(all P＞0.05). Conclusions: GH supplementation can improve the ovarian function and response, and clinical outcome for those non-DOR patients with previous IVF/ ICSI failure, especially for young patients. [ABSTRACT FROM AUTHOR]

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the improved effect of the Pen Yan Xiao enema on microcirculation in mice. Methods: Sixty adult mice were used. Ten mice were used as control group. Fifty mice were induced with the high-molecular dextran to develop animal models of microcirculation disturbance, and then randomly divided into 5 groups as follows, model group, three groups treated with Pen Yan Xiao enema liquid (2.5, 5.0, 10.0 g/kg), and a group treated with Chuanxiongzine as positive control. Microcirculation in mice was compared before treatment and 5, 10, 20, 30 min after treatment using the WX-9 microcirculation microscope and the microcirculation detection and analysis system. Those parameters were analyzed, including the diameter size of capillary, the blood flow velocity, the blood flow pattern and the red cell aggregation. Results: Pen Yan Xiao enema can improve microcirculation in the model mice in a dose-dependent manner and a time-dependent manner. In three treatment groups, the diameter size of capillary and the blood flow velocity were increased; the blood flow pattern was improved, while the red cell aggregation was decreased. Those effects of large doses (10.0 g/kg) of Pen Yan Xiao enema were significant (P<0.05). Conclusions: Pen Yan Xiao enema can significantly improve microcirculation in the animal model of microcirculation disturbance induced by high polymer dextran, suggesting the pharmacologic action of Pen Yan Xiao on microcirculation. [ABSTRACT FROM AUTHOR]

Objective: To compare the efficacy of conventional in vitro fertilization (IVF)and intracytoplasmic sperm injection (ICSI)in older patients with poor ovarian response. Methods:The data of 381 in vitro fertilization-embryo transfer (IVF-ET) cycles of older patients (≥ 40 years old)with poor ovarian response were analyzed retrospectively. Those cycles were divided into two groups, IVF group (conventional IVF, 200 cycles) and ICSI group (181 cycles). Fertilization rate and clinical pregnancy rate were compared between two groups. Results: The fertilization rate and clinical pregnancy rate in the IVF group were insignificantly higher than those in the ICSI group, while the rate of effective cycles and high quality embryos in the ICSI group were very limitedly higher than those in the IVF group. However, there were not statistically differences in those rats between two groups (P>0.05). Conclusions: ICSI treatment did not increase fertilization rate and clinical pregnancy rate in IVF-ET cycles in those patients at ≥ 40 years with poor ovaian response. [ABSTRACT FROM AUTHOR]