Search

Objective：To investigate probiotic supplementation on blood sugar and lipids in patients with polycystic ovary syndrome. Methods：A total of 60 PCOS patients visited our hospital from March 2015 to January 2016 were divided into observed group (probiotic supplementation) and control group (metformin), each group of 30 cases. Serum levels of Fasting blood sugar (FBS), total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), fasting serum insulin (FSI), luteotropic hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), progesterone (P), estradiol (E2), testosterone (T) was detected in this study; HOMA-IR were calculated in all patients. Results：Serum FBS, FSI, HOMA-IR, TG and VLDL leves in observed group were significantly decreased compared with control group after treatment (P＜0.05). After treatment, serum LH and T levels in observed group were lower than those before treatment (P＜0.05). In addition, probiotic supplementation in PCOS patients resulted in a significant reduction in weight and BMI compared with those patients without treatment. Conclusions：PCOS patients with probiotic supplementation have favourable effects on blood sugar, blood lipids and weight loss, which could alleviate PCOS and its associated complications development. [ABSTRACT FROM AUTHOR]