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Judgments of learning (JOL) are one of the most commonly used measures of metamemory. There is mixed evidence that eliciting JOLs while participants are studying word pairs influences their subsequent recall, a phenomenon known as reactivity. The majority of studies have found that positive reactivity occurs when word pairs are related. This finding suggests that when the final test is sensitive to the cues used to make a JOL (e.g., pair relatedness), a benefit to recall is observed. Here, in three experiments, JOL reactivity is examined in the presence of a salient, yet non-diagnostic cue—font size. The results show that when study time is limited and font size is made salient, eliciting JOLs impairs future recall. It is argued that JOLs prompt participants to evaluate salient cues in the learning environment to evaluate whether they will affect future recall. This increased processing of salient cues can impair recall if it comes at the expense of processing less salient but more informative cues. These findings suggest that the relevance to the test of the cues processed when JOLs are performed determines the direction of reactivity effects, with both positive and negative reactivity being possible depending on how diagnostic the salient metacognitive cues are for recall.