1. Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan.
- Author
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Chang L, Chiang B, Kao C, Wu M, Chen P, Berkhout B, Yang H, Huang L, Kawasaki Disease Research Group, Chang, Luan-Yin, Chiang, Bor-Luen, Kao, Chuan-Liang, Wu, Mei-Hwan, Chen, Pei-Jer, Berkhout, Ben, Yang, Hui-Ching, and Huang, Li-Min
- Abstract
We investigated whether infection with a novel human coronavirus (HCoV), called "New Haven coronavirus" (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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