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Start Over Author "Modesti, P. A." Journal journal of hypertension
25 results on '"Modesti, P. A."'

2. Blood pressure variability: methodological aspects, clinical relevance and practical indications for management - a European Society of Hypertension position paper∗

Author

Parati, Gianfranco, Bilo, Grzegorz, Kollias, Anastasios, Pengo, Martino, Ochoa, Juan Eugenio, Castiglioni, Paolo, Stergiou, George S., Mancia, Giuseppe, Asayama, Kei, Asmar, Roland, Avolio, Alberto, Caiani, Enrico G., De La Sierra, Alejandro, Dolan, Eamon, Grillo, Andrea, Guzik, Przemysław, Hoshide, Satoshi, Head, Geoffrey A., Imai, Yutaka, Juhanoja, Eeva, Kahan, Thomas, Kario, Kazuomi, Kotsis, Vasilios, Kreutz, Reinhold, Kyriakoulis, Konstantinos G., Li, Yan, Manios, Efstathios, Mihailidou, Anastasia S., Modesti, Pietro Amedeo, Omboni, Stefano, Palatini, Paolo, Persu, Alexandre, Protogerou, Athanasios D., Saladini, Francesca, Salvi, Paolo, Sarafidis, Pantelis, Torlasco, Camilla, Veglio, Franco, Vlachopoulos, Charalambos, and Zhang, Yuqing

Published
2023
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3. Lifestyle, psychological, socioeconomic and environmental factors and their impact on hypertension during the coronavirus disease 2019 pandemic

Author

Kreutz, Reinhold, Dobrowolski, Piotr, Prejbisz, Aleksander, Algharably, Engi A.E-H, Bilo, Grzegorz, Creutzig, Felix, Grassi, Guido, Kotsis, Vasilios, Lovic, Dragan, Lurbe, Empar, Modesti, Pietro A., Pappaccogli, Marco, Parati, Gianfranco, Persu, Alexandre, Polonia, Jorge, Rajzer, Marek, de Timary, Philippe, Weber, Thomas, Weisser, Burkhard, Tsioufis, Konstantinos, Mancia, Giuseppe, and Januszewicz, Andrzej

Published
2021
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4. [PP.12.09] MASKED-UNCONTROLLED HYPERTENSION MANAGEMENT BASED ON OFFICE BP OR ON OUT-OF-OFFICE (AMBULATORY) BP MEASUREMENT (MASTER)

Author

Parati, G., primary, Rosei, E. Agabiti, additional, Bakris, G., additional, Bilo, G., additional, Branzi, G., additional, Faria, T., additional, Mancia, G., additional, McManus, R., additional, Modesti, P., additional, Ochoa, J., additional, Omboni, S., additional, Pellegrini, D., additional, Redon, J., additional, Schmieder, R.E., additional, Soranna, D., additional, Stergiou, G.S., additional, Wijnmaalen, P., additional, Zambon, A., additional, and Zanchetti, A., additional

Published
2017
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15. NEW FINDINGS ON SEASONAL CHANGES IN BLOOD PRESSURE

Author

Modesti, P. A., primary, Orlandini, S., additional, Morabito, M., additional, Cecchi, L., additional, Lombardo, C., additional, Baldelli, G., additional, Fauzi, E., additional, Parati, G., additional, and Gensini, G. F., additional

Published
2004
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18. Impaired angiotensin II–extracellular signal-regulated kinase signaling in failing human ventricular myocytes

Author

Modesti, Pietro Amedeo, Serneri, Gian Gastone Neri, Gamberi, Tania, Boddi, Maria, Coppo, Mirella, Lucchese, Gianluca, Chiavarelli, Mario, Bottai, Giulia, Marino, Francesco, Gensini, Camilla Toz, Franco Gensini, Gian, and Modesti, Alessandra

Abstract

Angiotensin II was reported to induce insulin-like growth factor-I and endothelin-1 gene expression and peptide release by ventricular cardiomyocytes. However, the progression from cardiac hypertrophy to failure in humans is characterized by a reduced myocyte expression of insulin-like growth factor-I and endothelin-1, notwithstanding the enhanced cardiac generation of angiotensin II. In the present study we investigated the functional status of the signaling pathways responsible for angiotensin II-induced endothelin-1 and insulin-like growth factor-I formation in human ventricular myocytes isolated from patients with dilated (n19) or ischemic (n14) cardiomyopathy and nonfailing donor hearts (n6).

Published
2008
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19. Zofenopril or irbesartan plus hydrochlorothiazide in elderly patients with isolated systolic hypertension untreated or uncontrolled by previous treatment: a double-blind, randomized study

Author

Modesti, Pietro A., Omboni, Stefano, Taddei, Stefano, Ghione, Sergio, Portaluppi, Francesco, Pozzilli, Paolo, Volpe, Massimo, Arca, Marcello, Calabrò, Paolo, Fulgheri, Paolo L. Dessì, Bucci, Marco, Berra, Sergio, Villani, Giovanni Q., Vladoianu, Mircea, Popescu, Elena, Velican, Valerica G., and Pirvu, Octavian

Published
2016
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20. Cardiovascular risk assessment in low-resource settings

Author

Modesti, Pietro A., Agostoni, Piergiuseppe, Agyemang, Charles, Basu, Sanjay, Benetos, Athanase, Cappuccio, Francesco P., Ceriello, Antonio, Del Prato, Stefano, Kalyesubula, Robert, O’Brien, Eoin, Kilama, Michael O., Perlini, Stefano, Picano, Eugenio, Reboldi, Gianpaolo, Remuzzi, Giuseppe, Stuckler, David, Twagirumukiza, Marc, Bortel, Luc M. Van, Watfa, Ghassan, Zhao, Dong, and Parati, Gianfranco

Abstract

The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 confirms ischemic heart disease and stroke as the leading cause of death and that hypertension is the main associated risk factor worldwide. How best to respond to the rising prevalence of hypertension in resource-deprived settings is a topic of ongoing public-health debate and discussion. In low-income and middle-income countries, socioeconomic inequality and cultural factors play a role both in the development of risk factors and in the access to care. In Europe, cultural barriers and poor communication between health systems and migrants may limit migrants from receiving appropriate prevention, diagnosis, and treatment. To use more efficiently resources available and to make treatment cost-effective at the patient level, cardiovascular risk approach is now recommended. In 2011, The European Society of Hypertension established a Working Group on ‘Hypertension and Cardiovascular risk in low resource settings’, which brought together cardiologists, diabetologists, nephrologists, clinical trialists, epidemiologists, economists, and other stakeholders to review current strategies for cardiovascular risk assessment in population studies in low-income and middle-income countries, their limitations, possible improvements, and future interests in screening programs. This report summarizes current evidence and presents highlights of unmet needs.

Published
2014
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23. Psychological predictors of the antihypertensive effects of music-guided slow breathing

Author

Modesti, Pietro Amedeo, Ferrari, Antonella, Bazzini, Cristina, Costanzo, Giusi, Simonetti, Ignazio, Taddei, Stefano, Biggeri, Annibale, Parati, Gianfranco, Gensini, Gian Franco, and Sirigatti, Saulo

Abstract

The possibility that daily sessions of music-guided slow breathing may reduce 24-h ambulatory blood pressure (ABP), and predictors of efficacy were explored in a randomized, placebo-controlled trial with parallel design.

Published
2010
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24. Office and 24-h ambulatory blood pressure control by treatment in general practice the ‘Monitoraggio della pressione ARteriosa nella medicina TErritoriale’ study

Author

Zaninelli, Augusto, Parati, Gianfranco, Cricelli, Claudio, Bignamini, Angelo A, Modesti, Pietro A, Pamparana, Franco, Bilo, Grzegorz, Mancia, Giuseppe, and Gensini, Gian F

Abstract

Guidelines recommend that blood pressure (BP) should be lowered in hypertensive patients to prevent cardiovascular accidents. Management of antihypertensive treatment by general practitioners is usually based on office measurements, which may not allow an assessment of BP control over 24 h, which requires ambulatory BP monitoring (ABPM) to be implemented. This is rarely done in general practice, and limited information is available on the consistency between the evaluations of the response to treatment provided by office measurement and by ABPM in this setting.

Published
2010
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25. Office and 24-h ambulatory blood pressure control by treatment in general practice: the ‘Monitoraggio della pressione ARteriosa nella medicina TErritoriale’ study

Author

Giuseppe Mancia, Grzegorz Bilo, Claudio Cricelli, Angelo A. Bignamini, Pietro Amedeo Modesti, Augusto Zaninelli, Gianfranco Parati, Franco Pamparana, Gian F. Gensini, Zaninelli, A, Parati, G, Cricelli, C, Bignamini, A, Modesti, P, Pamparana, F, Bilo, G, Mancia, G, and Gensini, G

Subjects
Adult, Male, Blood pressure determination, medicine.medical_specialty, Ambulatory blood pressure, Physiology, Young Adult, Predictive Value of Tests, Internal Medicine, Humans, Medicine, Blood pressure monitoring, Intensive care medicine, Antihypertensive Agents, Aged, Aged, 80 and over, business.industry, Blood Pressure Monitoring, Ambulatory, Middle Aged, ambulatory blood pressure monitoring, hypertension, Blood pressure, Italy, Practice Guidelines as Topic, Hypertension, General practice, Female, Family Practice, Cardiology and Cardiovascular Medicine, business
Abstract

Background Guidelines recommend that blood pressure (BP) should be lowered in hypertensive patients to prevent cardiovascular accidents. Management of antihypertensive treatment by general practitioners is usually based on office measurements, which may not allow an assessment of BP control over 24 h, which requires ambulatory BP monitoring (ABPM) to be implemented. This is rarely done in general practice, and limited information is available on the consistency between the evaluations of the response to treatment provided by office measurement and by ABPM in this setting.Aim To assess concordance between office BP measurements and ABPM-based estimates of hypertension control in a general practice setting.Design of study Prospective, comparative between techniques.Setting General practice.Methods Seventy-eight general practices, representative of all Italian regions, participated in this study by recruiting sequential hypertensive adults on stabilized treatment, who were subdivided into even groups with office BP, respectively, controlled or noncontrolled by treatment. In each individual, ABPM was applied by the general practitioner after appropriate training, and 24-h ABP values were defined as controlled or not according to current guidelines. Concordance between office and ABPM evaluation of BP control was assessed with kappa statistics. Positive and negative predictive values of office measurement versus ABPM were estimated.Results Between July 2005 and November 2006, 190 general practitioners recruited 2059 hypertensive patients based on office BP measurements; in 1728 patients, a 24-h ABPM was performed, yielding 1524 recordings considered as valid for further analysis. The agreement between the assessment of BP control by office measurement and by ABPM was poor (kappa=0.120), with office measurements showing a satisfactory positive predictive value (0.842) and a poor negative predictive value (0.278); the situation was worse in patients with three or more among the following features: male sex, age of at least 65 years, alcohol consumption, diabetes, and obesity (negative predictive value=0.149).Conclusion In general practice, the agreement between assessment of BP control by treatment provided by office and ambulatory BP measurements is better in patients of 'uncontrolled' office BP than in 'controlled' office BP patients. This emphasizes the need for the larger use of out-of-office BP monitoring in a general practice setting, in particular, in patients considered as 'controlled' during consultation. J Hypertens 28:910-917 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

Published
2010
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