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Start Over Author "Douglas Guy" Journal journal of heterocyclic chemistry
1 results on '"Douglas Guy"'

1. Polyfunctional pyridines from nitroacetamidine and β-diketones. A useful synthesis of substituted imidazo [4,5-b] pyridines and related compounds

Author

Douglas Guy Batt and Gregory C. Houghton

Subjects
Chemistry, Organic Chemistry, Medicinal chemistry
Abstract

Nitroacetamidine undergoes a useful cyclocondensation with β-diketones to produce substituted 2-amino-3-nitropyridines. Use of an acylpyruvate generates hitherto unreported 2-amino-3-nitropyridine-4-carboxylates. These may be converted easily to functionalized imidazo[4,5-b]pyridines and oxazolo-[5,4-b]pyridines.

Published
1995

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