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17 years old male patient admitted to the emergency room of our hospital for unconsciousness, nausea, vomiting, and seizures story. During follow-up orotracheal intubation was performed because of respiratory arrest. At that time there were not any significant findings and the taken computed tomography were normal. There were not any diseases at the patient's history. After identifying positive high levels of methamphetamine in the urine, another detailed patient history taken from patient's parents. Assuming the patient's problem as being methamphetamine intoxication, the related threatment was given accordingly. In the control CT which was taken on the third day after admission (CT image); there were findings in favor of brain edema such as cerebral sulcus deletions. We began treating patient with sodium thiopental infusion, hyperventilation, mannitol, dexamethasone, took patient's head to the optimal position and began to phenytoin therapy for the control of seizures. Mechanical ventilation support was terminated and the patient was extubated during the 16th day of the treatment as laboratory findings got normal and the patient showed th adequate clinical improvement. He was discharged with healing from ICU on the 30 day. [ABSTRACT FROM AUTHOR]