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Background: Retroperitoneal hematoma presents with a diagnostic difficulty, especially when it does not present with acute symptoms. Lack of history of any previous intervention, such as femoral catheterization, can add to the diagnostic dilemma. Case: A 71-year-old woman was referred to the Gynaecology Oncology division of the Department of Obstetrics and Gynaecology at the National University Hospital, Singapore for suspected ovarian malignancy. Imaging studies showed a complex adnexal mass infiltrating into the recti muscles. A core biopsy from the mass was inconclusive. Results: Diagnostic laparoscopy confirmed a retroperitoneal hematoma, and the patient was managed conservatively. Conclusions: Retroperitoneal hematoma should be kept as a differential diagnosis of ill-defined pelvic masses with unclear imaging studies, especially in the setting of normal tumor markers and history of anticoagulation therapy. The role of fine needle aspiration cytology (FNAC) and diagnostic laparoscopy should b...

A prospective randomized study is presented of 161 patients with cervical intraepithelial neoplasia (CIN) comparing treatment either by "cold" coagulation or cryotherapy. Following colposcopy with directed biopsy confirmation of CIN, patients were randomized on the basis of their medical record numbers and received outpatient therapy. Seven patients were excluded from analysis of final cure rates. The follow-up period ranged from 3 months to 4 years, with 81% of subjects being followed for longer than 1 year. Of 154 patients assessable for cure following single or repeat treatment using the same modality, 89 had received cold coagulation and 65 cryotherapy. Final cure rates using cold coagulation were for CIN I 95.3%, CIN II 100%, and CIN III 92.6%; the overall cure rate for the three grades combined was 95.5%. In the 65 patients treated with cryotherapy, the final cure rates for CIN I, II, and III were 96.7%, 100%, and 84.2%, respectively, and overall, for the three grades combined, it was 93.8%...