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Background: The concomitant availability of services and care with the rise in the older population in India does not commensurate with their health care needs, thus affecting their well-being and quality of life (QoL). The Indian State of Kerala, epidemiologically and demographically advanced and often compared with developed countries, has the highest number of older persons. It also ranks top in the human development index in the country. This study seeks to explore the factors influencing QoL among older persons in Kerala, a state located within a low middle-income country. Materials and Methods: Qualitative methods using exploratory design were employed. Ten focus group discussions and ten face-to-face in-depth interviews were conducted in two districts of Kerala. The data were thematically analyzed using a framework approach. Results: The study explored a multitude of factors influencing QoL among older people in Kerala. The themes that emerged from the study were, "Financial securities and insecurities," "psychological well-being," "lifestyle," "health-care utilization," and "social engagement." Conclusion: The current study findings have explored the changing importance or value of the factors attributed to older persons' QoL in an advanced population within a low middle-income country such as India. [ABSTRACT FROM AUTHOR]