1. Enzootic nasal tumour of goats: demonstration of a type D-related retrovirus in nasal fluids and tumours.
- Author
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De las Heras M, Sharp JM, Garcia de Jalon JA, and Dewar P
- Subjects
- Animals, Blotting, Western veterinary, Goat Diseases enzymology, Goats, Nose Neoplasms enzymology, Nose Neoplasms microbiology, Nose Neoplasms ultrastructure, RNA-Directed DNA Polymerase metabolism, Retroviridae enzymology, Retroviridae ultrastructure, Retroviridae Infections microbiology, Retroviridae Infections veterinary, Goat Diseases microbiology, Nose Neoplasms veterinary, Retroviridae isolation & purification
- Abstract
Nasal exudate and tumour tissue from goats with enzootic nasal tumours were shown to contain a reverse transcriptase activity associated with a particle of buoyant density typical of retroviruses. The same particle contained a 25,000 Mr protein that cross-reacted with the p27 of Mason-Pfizer monkey virus (MPMV) and with p25 of sheep pulmonary adenomatosis retrovirus. It also contained a low Mr protein related to p10-12 of MPMV.
- Published
- 1991
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