Keywords: Chicago classification; High-resolution manometry; Esophageal motility disorders; Achalasia; Water-perfused catheter; Patient position EN Chicago classification High-resolution manometry Esophageal motility disorders Achalasia Water-perfused catheter Patient position 1084 1086 3 05/11/22 20220501 NES 220501 Introduction Chicago classification guides esophageal motility disorder classification.[1] The most recent version 4.0 (CC4)[2] also brings technical details on the performance of the test.[3] Supportive measures, including change in position from supine to upright, were incorporated.[4] Change in position does not affect pressure measurement by solid-state catheters. 1) and an in vivo test in a patient (female, 42 years old, complaining of dysphagia) with esophagogastric outflow obstruction (integrated relaxation pressure 21.8 mmHg) following the same protocol and also changing catheter location inside the patient (Fig. High-resolution manometry, Achalasia, Water-perfused catheter, Chicago classification, Esophageal motility disorders, Patient position. [Extracted from the article]