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This study assesses the antigenotoxic activity, antimutagenic and inhibiting cytotoxic conferred for the extract of seeds of Salvia hispanica L. (ShE) in culture of human leukocytes. Phytochemical methods were used by HPLC for determination of compounds: chlorogenic acid, caffeic acid, gallic acid, kaempferol, quercetin and rutin. Cellular cultures were placed in contact with the extract at concentrations of 100 µg/mL and 10 µg/mL in addition to hydrogen peroxide as causative agent of damage. The results showed a reversal rate of DNA damage of 31%, 41.4% in the frequency of micronuclei, 21.7% in cytoplasmic rates of chromosomal abnormalities and a 17.7% improvement in cell viability in the sample containing 100 µg/mL of ShE. The samples that contained the ShE in low concentration of 10 µg/mL did not show such reversals against the effects of H2O2. We demonstrated that the use of ShE has beneficial and promising effects.

The effects of supplementation with golden flaxseed for 28 days on anthropometric, blood pressure, biochemical and oxidative parameters in patients with metabolic syndrome (MS) were investigated. Twenty patients with MS and 24 healthy volunteers consumed 40 g of golden flaxseed daily for 28 days. Anthropometric and blood pressure measurements and fasting blood samples were taken before and after supplementation. Biochemical assays demonstrated significant reductions in lipid and glucose levels and cardiac, hepatic and kidney markers. Oxidative parameters showed significant reductions (p