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In our study, preoperative factors affecting the development of re-operation after lung resection were examined.413 patients who underwent lung resection between 2018-2020 were included in our study. The preoperative data of 25 (6.1%) patients who underwent re-operation and 388 (93.9%) patients who did not undergo re-operation were compared. Preoperative hemoglobin level (p=0.009), neoadjuvant therapy (p<0.001), pneumonectomy (p<0.001), thoracotomy (p=0.005), amount of intraoperative blood loss (p<0.001), need for intraoperative blood product use (p). =0.005), intraoperative mean arterial pressure (p=0.01), pulse rate (p=0.001), postoperative hemoglobulin amount (p<0.001) were found to affect and increase the probability of re-operation. It was statistically significant that the need for postoperative blood product usage was higher (p<0.001), postoperative complications (100% vs. 22.8%, p<0.001) and mortality (0.6% vs. 4%, p=0.01) in reoperated patients. It was found that the hospitalization day in the ICU was longer in those who underwent reoperation than in those who did not (3.2 days vs. 1.5, p<0.001). Independent risk factors affecting re-operation according to multiple logistic regression analysis; neoadjuvant treatment (p<0.001), operation time (p=0.04), intraoperative pulse rate (p=0.01) and postoperative hemoglobin (p<0.001) were found. Low preoperative hemoglobin level, on the other hand, independently affected the development of re-operation at a level close to significance (p=0.06). Re-operation due to bleeding after lung resection increases the rate of cardiopulmonary complications in the postoperative period. Careful follow-up and approach of surgery and anesthesia in the intraoperative period will contribute to the decrease in the incidence of re-operation. [ABSTRACT FROM AUTHOR]