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Start Over Author "You Min Sohn" Journal journal of ethnopharmacology
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1. Analysis of strychnine from detoxified Strychnos nux-vomica [corrected] seeds using liquid chromatography-electrospray mass spectrometry

Author

Chul Young Kim, Jinwoong Kim, You-Min Sohn, Kwan Yul Oh, and Young Hae Choi

Subjects
Pharmacology, Electrospray, Spectrometry, Mass, Electrospray Ionization, Brucine, Chromatography, biology, Plant Extracts, Alkaloid, Strychnos nux-vomica, Strychnos, Strychnine, biology.organism_classification, Mass spectrometry, High-performance liquid chromatography, chemistry.chemical_compound, chemistry, Drug Discovery, Seeds
Abstract

The content of strychnine from Strychnos nux-vomica [corrected] seeds was analyzed and compared to processed seeds by the HPLC-ESI/MS method. Using this technique, levels as low as 1 ng of strychnine were detected. In contrast to conventional UV detectors, this method also made it possible to discriminate brucine. This study resulted in finding the content of strychnine in detoxified seeds to be one tenth of unprocessed Strychnos nux-vomica [corrected] seeds.

Published
2003

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